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PEX11β induces peroxisomal gene expression and alters peroxisome number during early Xenopus laevis development

Overview of attention for article published in BMC Developmental Biology, April 2011
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Title
PEX11β induces peroxisomal gene expression and alters peroxisome number during early Xenopus laevis development
Published in
BMC Developmental Biology, April 2011
DOI 10.1186/1471-213x-11-24
Pubmed ID
Authors

Mark A Fox, Logan A Walsh, Michelle Nieuwesteeg, Sashko Damjanovski

Abstract

Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen species elimination have contributed much attention in understanding their origin and biogenesis. Many studies have shown that de novo peroxisome biogenesis is an important regulatory process, while yeast studies suggest that total peroxisome numbers are in part regulated by proteins such as Pex11, which can facilitate the division of existing peroxisomes. Although de novo biogenesis and divisions are likely important mechanisms, the regulation of peroxisome numbers during embryonic development is poorly understood. Peroxisome number and function are particularly crucial in oviparous animals such as frogs where large embryonic yolk and fatty acid stores must be quickly metabolized, and resulting reactive oxygen species eliminated. Here we elucidate the role of Pex11β in regulating peroxisomal gene expression and number in Xenopus laevis embryogenesis.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Korea, Republic of 1 6%
Unknown 16 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 28%
Student > Ph. D. Student 3 17%
Student > Bachelor 2 11%
Student > Master 2 11%
Other 1 6%
Other 3 17%
Unknown 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 39%
Biochemistry, Genetics and Molecular Biology 6 33%
Medicine and Dentistry 1 6%
Unknown 4 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2011.
All research outputs
#18,297,449
of 22,653,392 outputs
Outputs from BMC Developmental Biology
#304
of 369 outputs
Outputs of similar age
#95,523
of 109,914 outputs
Outputs of similar age from BMC Developmental Biology
#4
of 4 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.