Title |
Mitochondrial responses to extreme environments: insights from metabolomics
|
---|---|
Published in |
Extreme Physiology & Medicine, May 2015
|
DOI | 10.1186/s13728-015-0026-9 |
Pubmed ID | |
Authors |
Katie A O’Brien, Julian L Griffin, Andrew J Murray, Lindsay M Edwards |
Abstract |
Humans are capable of survival in a remarkable range of environments, including the extremes of temperature and altitude as well as zero gravity. Investigation into physiological function in response to such environmental stresses may help further our understanding of human (patho-) physiology both at a systems level and in certain disease states, making it a highly relevant field of study. This review focuses on the application of metabolomics in assessing acclimatisation to these states, particularly the insights this approach can provide into mitochondrial function. It includes an overview of metabolomics and the associated analytical tools and also suggests future avenues of research. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 67% |
Japan | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 83% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 4% |
Unknown | 53 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 16% |
Student > Master | 9 | 16% |
Researcher | 7 | 13% |
Student > Bachelor | 4 | 7% |
Student > Doctoral Student | 3 | 5% |
Other | 11 | 20% |
Unknown | 12 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 22% |
Medicine and Dentistry | 9 | 16% |
Sports and Recreations | 6 | 11% |
Biochemistry, Genetics and Molecular Biology | 5 | 9% |
Chemistry | 3 | 5% |
Other | 6 | 11% |
Unknown | 14 | 25% |