Title |
Nutrigenomics in honey bees: digital gene expression analysis of pollen's nutritive effects on healthy and varroa-parasitized bees
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Published in |
BMC Genomics, October 2011
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DOI | 10.1186/1471-2164-12-496 |
Pubmed ID | |
Authors |
Cédric Alaux, Christelle Dantec, Hughes Parrinello, Yves Le Conte |
Abstract |
Malnutrition is a major factor affecting animal health, resistance to disease and survival. In honey bees (Apis mellifera), pollen, which is the main dietary source of proteins, amino acids and lipids, is essential to adult bee physiological development while reducing their susceptibility to parasites and pathogens. However, the molecular mechanisms underlying pollen's nutritive impact on honey bee health remained to be determined. For that purpose, we investigated the influence of pollen nutrients on the transcriptome of worker bees parasitized by the mite Varroa destructor, known for suppressing immunity and decreasing lifespan. The 4 experimental groups (control bees without a pollen diet, control bees fed with pollen, varroa-parasitized bees without a pollen diet and varroa-parasitized bees fed with pollen) were analyzed by performing a digital gene expression (DGE) analysis on bee abdomens. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 33% |
Germany | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 83% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 4 | 1% |
Germany | 2 | <1% |
Mexico | 2 | <1% |
United Kingdom | 1 | <1% |
Chile | 1 | <1% |
France | 1 | <1% |
Poland | 1 | <1% |
Unknown | 269 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 62 | 22% |
Researcher | 38 | 14% |
Student > Master | 29 | 10% |
Student > Bachelor | 29 | 10% |
Student > Doctoral Student | 19 | 7% |
Other | 50 | 18% |
Unknown | 54 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 136 | 48% |
Biochemistry, Genetics and Molecular Biology | 27 | 10% |
Environmental Science | 14 | 5% |
Veterinary Science and Veterinary Medicine | 10 | 4% |
Medicine and Dentistry | 8 | 3% |
Other | 20 | 7% |
Unknown | 66 | 23% |