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Identification of a novel temperature sensitive promoter in cho cells

Overview of attention for article published in BMC Biotechnology, May 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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1 X user
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2 patents

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99 Mendeley
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Title
Identification of a novel temperature sensitive promoter in cho cells
Published in
BMC Biotechnology, May 2011
DOI 10.1186/1472-6750-11-51
Pubmed ID
Authors

Haruthai Thaisuchat, Martina Baumann, Jens Pontiller, Friedemann Hesse, Wolfgang Ernst

Abstract

The Chinese hamster ovary (CHO) expression system is the leading production platform for manufacturing biopharmaceuticals for the treatment of numerous human diseases. Efforts to optimize the production process also include the genetic construct encoding the therapeutic gene. Here we report about the successful identification of an endogenous highly active gene promoter obtained from CHO cells which shows conditionally inducible gene expression at reduced temperature.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 3 3%
United States 2 2%
Germany 1 1%
Slovenia 1 1%
Unknown 92 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 28 28%
Researcher 21 21%
Student > Doctoral Student 10 10%
Student > Master 7 7%
Student > Bachelor 6 6%
Other 13 13%
Unknown 14 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 38 38%
Biochemistry, Genetics and Molecular Biology 28 28%
Engineering 8 8%
Chemical Engineering 4 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 3 3%
Unknown 15 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2020.
All research outputs
#4,481,876
of 22,653,392 outputs
Outputs from BMC Biotechnology
#245
of 935 outputs
Outputs of similar age
#22,810
of 109,649 outputs
Outputs of similar age from BMC Biotechnology
#4
of 19 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 935 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,649 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.