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Anti-CCL2: building a reservoir or opening the floodgates to metastasis?

Overview of attention for article published in Breast Cancer Research, May 2015
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19 Mendeley
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Title
Anti-CCL2: building a reservoir or opening the floodgates to metastasis?
Published in
Breast Cancer Research, May 2015
DOI 10.1186/s13058-015-0573-4
Pubmed ID
Authors

Jessica R Hitchcock, Christine J Watson

Abstract

Neutralisation of macrophage chemoattractant C-C chemokine ligand 2 (CCL2) has shown reduced metastasis and enhanced survival in numerous experimental models of tumorigenesis. However, important new findings reported in Nature by Momo Bentires-Alj's laboratory demonstrate that withdrawal of anti-CCL2 treatment accelerates lung metastasis and death in mice. The study highlights the need to consider longer term consequences of therapeutic intervention of metastatic disease, especially with regard to transient interference with the tumour microenvironment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 42%
Professor 3 16%
Student > Doctoral Student 2 11%
Researcher 2 11%
Student > Master 2 11%
Other 1 5%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 7 37%
Biochemistry, Genetics and Molecular Biology 4 21%
Agricultural and Biological Sciences 3 16%
Immunology and Microbiology 1 5%
Engineering 1 5%
Other 0 0%
Unknown 3 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2016.
All research outputs
#16,046,765
of 25,371,288 outputs
Outputs from Breast Cancer Research
#1,429
of 2,052 outputs
Outputs of similar age
#149,361
of 280,390 outputs
Outputs of similar age from Breast Cancer Research
#24
of 38 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,390 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.