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Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedside

Overview of attention for article published in Autoimmunity Highlights, August 2014
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77 Mendeley
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Title
Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedside
Published in
Autoimmunity Highlights, August 2014
DOI 10.1007/s13317-014-0058-y
Pubmed ID
Authors

D. Squatrito, G. Emmi, E. Silvestri, L. Ciucciarelli, M. M. D’Elios, D. Prisco, L. Emmi

Abstract

Systemic lupus erythematosus (SLE) is considered an autoimmune disease with multiorgan involvement. Many advances have been made during the last decade regarding inflammatory pathways, genetic and epigenetic alterations, adaptive and innate immune system mechanisms specifically involved in SLE pathogenesis. Apoptosis has been proposed as an important player in SLE pathogenesis more than a decade ago. However, only recently new key apoptotic pathways have been investigated and the link between apoptotic debris containing autoantigens, innate immunity and ongoing inflammation has been further elucidated. Better understanding of cellular mechanisms and involved cytokines contributed to the development of new biological drugs specifically addressed for SLE therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 77 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 18%
Student > Master 13 17%
Student > Ph. D. Student 9 12%
Other 8 10%
Student > Doctoral Student 5 6%
Other 14 18%
Unknown 14 18%
Readers by discipline Count As %
Medicine and Dentistry 33 43%
Agricultural and Biological Sciences 13 17%
Biochemistry, Genetics and Molecular Biology 8 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Immunology and Microbiology 2 3%
Other 1 1%
Unknown 16 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2015.
All research outputs
#13,436,543
of 22,807,037 outputs
Outputs from Autoimmunity Highlights
#40
of 85 outputs
Outputs of similar age
#110,038
of 231,309 outputs
Outputs of similar age from Autoimmunity Highlights
#1
of 2 outputs
Altmetric has tracked 22,807,037 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 85 research outputs from this source. They receive a mean Attention Score of 4.2. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,309 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them