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Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China

Overview of attention for article published in Antimicrobial Resistance & Infection Control, May 2018
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Title
Prevalence and patterns of drug resistance among pulmonary tuberculosis patients in Hangzhou, China
Published in
Antimicrobial Resistance & Infection Control, May 2018
DOI 10.1186/s13756-018-0348-7
Pubmed ID
Authors

Qingchun Li, Gang Zhao, Limin Wu, Min Lu, Wei Liu, Yifei Wu, Le Wang, Ke Wang, Han-Zhu Qian, Li Xie

Abstract

To evaluate prevalence and patterns of drug resistance among pulmonary tuberculosis (TB) patients in Hangzhou City, China. Sputum samples of smear positive TB patients enrolled in 2011 and 2015 were collected and tested for drug susceptibility, and demographic and medical record data were extracted from the electronic database of China Information System for Disease Control and Prevention. Chi-square test was used to compare drug resistance prevalence between new and treated patients and between male and female patients, and Chi-square test for trend was used to compare the prevalence over calendar years 2011 and 2015. Of 1326 patients enrolled in 2015, 22.3% had resistance to any first-line anti-TB drugs and 8.0% had multi-drug resistance (MDR); drug resistance rates among previously treated cases were significantly higher than among new cases. Significant declines of resistance to isoniazid, rifampin, ethambutol and streptomycin, and MDR from 2011 to 2015 were observed among previously treated patients, while a significant decline of resistance to rifampin was observed among new cases. While the prevalence of acquired drug resistance decreased due to due to implementation of DOTS-Plus program, the prevalence of primary drug resistance due to transmission remained high. Greater efforts should be made to screen drug resistance for case finding and to reduce transmission through improving the treatment and management of drug-resistant patients.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 14%
Student > Bachelor 9 12%
Student > Doctoral Student 6 8%
Student > Postgraduate 4 5%
Lecturer 3 4%
Other 9 12%
Unknown 32 44%
Readers by discipline Count As %
Medicine and Dentistry 20 27%
Immunology and Microbiology 4 5%
Biochemistry, Genetics and Molecular Biology 4 5%
Nursing and Health Professions 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 8%
Unknown 34 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2019.
All research outputs
#15,115,997
of 24,003,070 outputs
Outputs from Antimicrobial Resistance & Infection Control
#963
of 1,347 outputs
Outputs of similar age
#188,459
of 329,847 outputs
Outputs of similar age from Antimicrobial Resistance & Infection Control
#30
of 35 outputs
Altmetric has tracked 24,003,070 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,347 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,847 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.