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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Fate of Antibody-Drug Conjugates in Cancer Cells
|
|---|---|
| Published in |
Journal of Experimental & Clinical Cancer Research, February 2018
|
| DOI | 10.1186/s13046-017-0667-1 |
| Pubmed ID | |
| Authors |
Cécile Chalouni, Sophia Doll |
| Abstract |
Antibody-Drug Conjugates (ADCs) are a class of cancer therapeutics that combines antigen specificity and potent cytotoxicity in a single molecule as they are comprised of an engineered antibody linked chemically to a cytotoxic drug. Four ADCs have received approval by the Food and Drug Administration (FDA) and the European Medicine Agency (EMA) and can be prescribed for metastatic conditions while around 60 ADCs are currently enrolled in clinical trials. The efficacy of an ADC greatly relies on its intracellular trafficking and processing of its components to trigger tumor cell death. A limited number of studies have addressed these critical processes that both challenge and help foster the design of ADCs. This review highlights those mechanisms and their relevance for future development of ADCs as cancer therapeutics. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 261 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 261 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 49 | 19% |
| Researcher | 34 | 13% |
| Student > Bachelor | 31 | 12% |
| Student > Master | 27 | 10% |
| Other | 22 | 8% |
| Other | 37 | 14% |
| Unknown | 61 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 58 | 22% |
| Chemistry | 42 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 9% |
| Agricultural and Biological Sciences | 22 | 8% |
| Medicine and Dentistry | 18 | 7% |
| Other | 29 | 11% |
| Unknown | 69 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2024.
All research outputs
#7,963,683
of 25,382,440 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#505
of 2,380 outputs
Outputs of similar age
#150,392
of 446,116 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#13
of 41 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 2,380 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,116 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.