Title |
Creutzfeldt-Jakob disease with Alzheimer pathology, presenting with status epilepticus following repeated partial seizures: a case report and literature review
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Published in |
BMC Neurology, April 2018
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DOI | 10.1186/s12883-018-1055-y |
Pubmed ID | |
Authors |
Keita Miyake, Takashi Hara, Etsuko Oshima, Kiyohiro Kawada, Hideki Ishizu, Yuko Yamauchi, Katsuya Satoh, Tetsuyuki Kitamoto, Shintaro Takenoshita, Seishi Terada, Norihito Yamada |
Abstract |
Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding. We experienced an elderly woman who presented initially with status epilepticus following repeated partial seizures in the course of Alzheimer disease (AD) dementia. Anti-convulsive therapy had no effect. Autopsy revealed definite CJD with AD pathology. This is the first reported CJD case presenting with status epilepticus in the course of AD dementia. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 15% |
Student > Master | 6 | 13% |
Student > Bachelor | 5 | 10% |
Student > Ph. D. Student | 4 | 8% |
Other | 3 | 6% |
Other | 9 | 19% |
Unknown | 14 | 29% |
Readers by discipline | Count | As % |
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Neuroscience | 5 | 10% |
Nursing and Health Professions | 4 | 8% |
Psychology | 3 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 5 | 10% |
Unknown | 16 | 33% |