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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Type 2 diabetes mellitus and myocardial ischemic preconditioning in symptomatic coronary artery disease patients
|
|---|---|
| Published in |
Cardiovascular Diabetology, May 2015
|
| DOI | 10.1186/s12933-015-0228-x |
| Pubmed ID | |
| Authors |
Paulo Cury Rezende, Rosa Maria Rahmi, Augusto Hiroshi Uchida, Leandro Menezes Alves da Costa, Thiago Luis Scudeler, Cibele Larrosa Garzillo, Eduardo Gomes Lima, Carlos Alexandre Wainrober Segre, Priscyla Girardi, Myrthes Takiuti, Marcela Francisca Silva, Whady Hueb, Jose Antonio Franchini Ramires, Roberto Kalil Filho |
| Abstract |
The influence of diabetes mellitus on myocardial ischemic preconditioning is not clearly defined. Experimental studies are conflicting and human studies are scarce and inconclusive. Identify whether diabetes mellitus intervenes on ischemic preconditioning in symptomatic coronary artery disease patients. Symptomatic multivessel coronary artery disease patients with preserved systolic ventricular function and a positive exercise test underwent two sequential exercise tests to demonstrate ischemic preconditioning. Ischemic parameters were compared among patients with and without type 2 diabetes mellitus. Ischemic preconditioning was considered present when the time to 1.0 mm ST deviation and rate pressure-product were greater in the second of 2 exercise tests. Sequential exercise tests were analyzed by 2 independent cardiologists. Of the 2,140 consecutive coronary artery disease patients screened, 361 met inclusion criteria, and 174 patients (64.2 ± 7.6 years) completed the study protocol. Of these, 86 had the diagnosis of type 2 diabetes. Among diabetic patients, 62 (72 %) manifested an improvement in ischemic parameters consistent with ischemic preconditioning, whereas among nondiabetic patients, 60 (68 %) manifested ischemic preconditioning (p = 0.62). The analysis of patients who demonstrated ischemic preconditioning showed similar improvement in the time to 1.0 mm ST deviation between diabetic and nondiabetic groups (79.4 ± 47.6 vs 65.5 ± 36.4 s, respectively, p = 0.12). Regarding rate pressure-product, the improvement was greater in diabetic compared to nondiabetic patients (3011 ± 2430 vs 2081 ± 2139 bpm x mmHg, respectively, p = 0.01). In this study, diabetes mellitus was not associated with impairment in ischemic preconditioning in symptomatic coronary artery disease patients. Furthermore, diabetic patients experienced an improvement in this significant mechanism of myocardial protection. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 22% |
| Student > Ph. D. Student | 4 | 13% |
| Student > Master | 4 | 13% |
| Student > Bachelor | 3 | 9% |
| Professor | 2 | 6% |
| Other | 6 | 19% |
| Unknown | 6 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 34% |
| Sports and Recreations | 4 | 13% |
| Agricultural and Biological Sciences | 2 | 6% |
| Nursing and Health Professions | 1 | 3% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 10 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2015.
All research outputs
#20,274,720
of 22,807,037 outputs
Outputs from Cardiovascular Diabetology
#1,213
of 1,379 outputs
Outputs of similar age
#223,290
of 267,111 outputs
Outputs of similar age from Cardiovascular Diabetology
#26
of 34 outputs
Altmetric has tracked 22,807,037 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,379 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.