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Mendeley readers
Attention Score in Context
| Title |
Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
|
|---|---|
| Published in |
Journal of Translational Medicine, May 2018
|
| DOI | 10.1186/s12967-018-1485-8 |
| Pubmed ID | |
| Authors |
Zhaofeng Jia, Qisong Liu, Yujie Liang, Xingfu Li, Xiao Xu, Kan Ouyang, Jianyi Xiong, Daping Wang, Li Duan |
| Abstract |
The role of rabbit synovial fluid-derived mesenchymal stem cells (rbSF-MSCs) in cartilage defect repair remains undefined. This work evaluates the in vivo effects of rbSF-MSCs to repair knee articular cartilage defects in a rabbit model. Cartilage defects were made in the patellar grooves of New Zealand white rabbits. The rbSF-MSCs were generated from the knee cavity by arthrocentesis. Passage 5 rbSF-MSCs were assayed by flow cytometry. The multipotency of rbSF-MSCs was confirmed after 3 weeks induction in vitro and the autologous rbSF-MSCs and predifferentiated rbSF-MSCs were injected into the synovial cavity. The intra-articular injection was performed once a week for 4 weeks. The animals were euthanized and the articular surfaces were subjected to macroscopic and histological evaluations at 8 and 12 weeks after the first intra-articular injection. Hyaline-like cartilage was detected in the defects treated with rbSF-MSCs, while fibrocartilage tissue formed in the defects treated with chondrocytes induced from rbSF-MSCs. Our results suggest that autologous undifferentiated rbSF-MSCs are favorable to articular cartilage regeneration in treating cartilage defects. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 73 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 22% |
| Student > Ph. D. Student | 14 | 19% |
| Researcher | 11 | 15% |
| Student > Bachelor | 6 | 8% |
| Student > Postgraduate | 4 | 5% |
| Other | 8 | 11% |
| Unknown | 14 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 25% |
| Biochemistry, Genetics and Molecular Biology | 10 | 14% |
| Agricultural and Biological Sciences | 4 | 5% |
| Engineering | 4 | 5% |
| Veterinary Science and Veterinary Medicine | 3 | 4% |
| Other | 13 | 18% |
| Unknown | 21 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2022.
All research outputs
#7,201,003
of 22,759,618 outputs
Outputs from Journal of Translational Medicine
#1,155
of 3,979 outputs
Outputs of similar age
#125,719
of 326,510 outputs
Outputs of similar age from Journal of Translational Medicine
#17
of 94 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,979 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,510 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.