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Mendeley readers
Attention Score in Context
| Title |
Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis
|
|---|---|
| Published in |
Critical Care, August 2010
|
| DOI | 10.1186/cc9098 |
| Pubmed ID | |
| Authors |
Helen F Galley |
| Abstract |
Development of organ dysfunction associated with sepsis is now accepted to be due at least in part to oxidative damage to mitochondria. Under normal circumstances, complex interacting antioxidant defense systems control oxidative stress within mitochondria. However, no studies have yet provided conclusive evidence of the beneficial effect of antioxidant supplementation in patients with sepsis. This may be because the antioxidants are not accumulating in the mitochondria, where they are most needed. Antioxidants can be targeted selectively to mitochondria by several means. This review describes the in vitro studies and animal models of several diseases involving oxidative stress, including sepsis, in which antioxidants targeted at mitochondria have shown promise, and the future implications for such approaches in patients. |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 3% |
| Brazil | 2 | 2% |
| France | 1 | <1% |
| Indonesia | 1 | <1% |
| Chile | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 101 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 15% |
| Student > Ph. D. Student | 16 | 15% |
| Researcher | 15 | 14% |
| Student > Bachelor | 11 | 10% |
| Student > Doctoral Student | 10 | 9% |
| Other | 27 | 25% |
| Unknown | 14 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 44% |
| Agricultural and Biological Sciences | 23 | 21% |
| Biochemistry, Genetics and Molecular Biology | 11 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Chemistry | 3 | 3% |
| Other | 6 | 5% |
| Unknown | 15 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2022.
All research outputs
#3,008,257
of 25,371,288 outputs
Outputs from Critical Care
#2,513
of 6,554 outputs
Outputs of similar age
#11,729
of 104,652 outputs
Outputs of similar age from Critical Care
#5
of 35 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,652 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.