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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effect of increased enteral protein intake on plasma and urinary urea concentrations in preterm infants born at < 32 weeks gestation and < 1500 g birth weight enrolled in a randomized controlled trial – a secondary analysis
|
|---|---|
| Published in |
BMC Pediatrics, May 2018
|
| DOI | 10.1186/s12887-018-1136-5 |
| Pubmed ID | |
| Authors |
Michaela Mathes, Christoph Maas, Christine Bleeker, Julia Vek, Wolfgang Bernhard, Andreas Peter, Christian F. Poets, Axel R. Franz |
| Abstract |
Feeding breast milk is associated with reduced morbidity and mortality, as well as improved neurodevelopmental outcome but does not meet the high nutritional requirements of preterm infants. Both plasma and urinary urea concentrations represent amino acid oxidation and low concentrations may indicate insufficient protein supply. This study assesses the effect of different levels of enteral protein on plasma and urinary urea concentrations and determines if the urinary urea-creatinine ratio provides reliable information about the protein status of preterm infants. Sixty preterm infants (birthweight < 1500 g; gestational age < 32 weeks) were enrolled in a randomized controlled trial and assigned to either a lower-protein group (median protein intake 3.7 g/kg/d) or a higher-protein group (median protein intake 4,3 g/kg/d). Half the patients in the higher-protein group received standardized supplementation with a supplement adding 1.8 g protein/100 ml milk, the other half received individual supplementation depending on the respective mother's milk macronutrient content. Plasma urea concentration was determined in two scheduled blood samples (BS1; BS2); urinary urea and creatinine concentrations in weekly spot urine samples. The higher-protein group showed higher plasma urea concentrations in both BS1 and BS2 and a higher urinary urea-creatinine-ratio in week 3 and 5-7 compared to the lower-protein group. In addition, a highly positive correlation between plasma urea concentrations and the urinary urea-creatinine-ratio (p < 0.0001) and between actual protein intake and plasma urea concentrations and the urinary urea-creatinine-ratio (both p < 0.0001) was shown. The urinary urea-creatinine-ratio, just like plasma urea concentrations, may help to estimate actual protein supply, absorption and oxidation in preterm infants and, additionally, can be determined non-invasively. Further investigations are needed to determine reliable cut-off values of urinary urea concentrations to ensure appropriate protein intake. Clinicaltrials.gov; NCT01773902 registered 15 January 2013, retrospectively registered. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 120 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 10 | 8% |
| Student > Ph. D. Student | 8 | 7% |
| Researcher | 8 | 7% |
| Student > Master | 7 | 6% |
| Student > Postgraduate | 6 | 5% |
| Other | 28 | 23% |
| Unknown | 53 | 44% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 23% |
| Nursing and Health Professions | 18 | 15% |
| Unspecified | 10 | 8% |
| Social Sciences | 2 | 2% |
| Agricultural and Biological Sciences | 2 | 2% |
| Other | 3 | 3% |
| Unknown | 58 | 48% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2018.
All research outputs
#17,948,821
of 23,047,237 outputs
Outputs from BMC Pediatrics
#2,293
of 3,042 outputs
Outputs of similar age
#237,592
of 327,709 outputs
Outputs of similar age from BMC Pediatrics
#65
of 67 outputs
Altmetric has tracked 23,047,237 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,042 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,709 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.