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X Demographics
Mendeley readers
| Title |
Noninferiority trials
|
|---|---|
| Published in |
Trials, July 2000
|
| DOI | 10.1186/cvm-1-1-019 |
| Pubmed ID | |
| Authors |
Steven M Snapinn |
| Abstract |
Noninferiority trials are intended to show that the effect of a new treatment is not worse than that of an active control by more than a specified margin. These trials have a number of inherent weaknesses that superiority trials do not: no internal demonstration of assay sensitivity, no single conservative analysis approach, lack of protection from bias by blinding, and difficulty in specifying the noninferiority margin. Noninferiority trials may sometimes be necessary when a placebo group can not be ethically included, but it should be recognized that the results of such trials are not as credible as those from a superiority trial. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 30% |
| United Kingdom | 2 | 20% |
| Mexico | 1 | 10% |
| Unknown | 4 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 50% |
| Practitioners (doctors, other healthcare professionals) | 3 | 30% |
| Scientists | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 165 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| Indonesia | 1 | <1% |
| Chile | 1 | <1% |
| United Kingdom | 1 | <1% |
| Tunisia | 1 | <1% |
| Canada | 1 | <1% |
| Brazil | 1 | <1% |
| Argentina | 1 | <1% |
| Egypt | 1 | <1% |
| Other | 2 | 1% |
| Unknown | 151 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 34 | 21% |
| Student > Ph. D. Student | 20 | 12% |
| Student > Master | 18 | 11% |
| Other | 14 | 8% |
| Professor > Associate Professor | 12 | 7% |
| Other | 45 | 27% |
| Unknown | 22 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 87 | 53% |
| Agricultural and Biological Sciences | 12 | 7% |
| Nursing and Health Professions | 6 | 4% |
| Psychology | 5 | 3% |
| Mathematics | 5 | 3% |
| Other | 24 | 15% |
| Unknown | 26 | 16% |