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X Demographics
Mendeley readers
| Title |
Withdrawal of cerivastatin from the world market
|
|---|---|
| Published in |
Trials, September 2001
|
| DOI | 10.1186/cvm-2-5-205 |
| Pubmed ID | |
| Authors |
Curt D Furberg, Bertram Pitt |
| Abstract |
Cerivastatin was recently withdrawn from the market because of 52 deaths attributed to drug-related rhabdomyolysis that lead to kidney failure. The risk was found to be higher among patients who received the full dose (0.8 mg/day) and those who received gemfibrozil concomitantly. Rhabdomyolysis was 10 times more common with cerivastatin than the other five approved statins. We address three important questions raised by this withdrawal. Should we continue to approve drugs on surrogate efficacy? Are all statins interchangeable? Do the benefits outweigh the risks of statins? We conclude that decisions regarding the use of drugs should be based on direct evidence from long-term clinical outcome trials. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 9% |
| Netherlands | 1 | 9% |
| Unknown | 9 | 82% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 73% |
| Scientists | 2 | 18% |
| Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 207 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Sweden | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 202 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 39 | 19% |
| Student > Bachelor | 38 | 18% |
| Student > Ph. D. Student | 29 | 14% |
| Researcher | 21 | 10% |
| Student > Doctoral Student | 15 | 7% |
| Other | 26 | 13% |
| Unknown | 39 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 18% |
| Medicine and Dentistry | 35 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 35 | 17% |
| Biochemistry, Genetics and Molecular Biology | 28 | 14% |
| Chemistry | 9 | 4% |
| Other | 14 | 7% |
| Unknown | 49 | 24% |