Title |
Staphylococcus aureus and Chronic Airway Disease
|
---|---|
Published in |
World Allergy Organization Journal, August 2010
|
DOI | 10.1097/wox.0b013e3181ecd8ae |
Pubmed ID | |
Authors |
Lara Derycke, Claudina Pérez-Novo, Koen Van Crombruggen, Marie-Noëlle Corriveau, Claus Bachert |
Abstract |
Staphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. This inflammation of the upper airways is characterized by a T-helper 2-driven disease: interleukin-5 is significantly increased and local production of immunoglobulin E is observed. S. aureus and its enterotoxins are deregulating the tissue inflammation at different levels: structural cells and the innate and adaptive immune system. Knowing the triggers of the pathomechanisms involved will greatly help us to find new therapeutic approaches to resolve this chronic inflammatory process. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 150% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
India | 1 | 3% |
Unknown | 29 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 23% |
Student > Bachelor | 5 | 16% |
Student > Ph. D. Student | 5 | 16% |
Student > Master | 2 | 6% |
Lecturer > Senior Lecturer | 1 | 3% |
Other | 2 | 6% |
Unknown | 9 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 32% |
Medicine and Dentistry | 8 | 26% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Immunology and Microbiology | 2 | 6% |
Arts and Humanities | 1 | 3% |
Other | 1 | 3% |
Unknown | 7 | 23% |