Title |
In vitro antimicrobial susceptibility testing of human Brucella melitensis isolates from Qatar between 2014 – 2015
|
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Published in |
BMC Microbiology, June 2015
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DOI | 10.1186/s12866-015-0458-9 |
Pubmed ID | |
Authors |
Anand Deshmukh, Ferry Hagen, Ola Al Sharabasi, Mariamma Abraham, Godwin Wilson, Sanjay Doiphode, Muna Al Maslamani, Jacques F Meis |
Abstract |
Brucellosis is one of the most common zoonotic disease affecting humans and animals and is endemic in many parts of the world including the Gulf Cooperation Council region (GCC). The aim of this study was to identify the species and determine the antimicrobial susceptibility pattern of Brucella strains isolated from clinical specimens, from Qatar. We evaluated 231 Brucella isolates. All isolates were identified as B. melitensis. All the isolates were susceptible to doxycycline, tetracycline, streptomycin, gentamicin, trimethoprim / sulfamethoxazole and ciprofloxacin except rifampicin, where 48 % of the strains showed elevated MICs (>1 mg/L). The rifampicin-resistance related hotspots within the rpoB gene were amplified and sequenced using PCR and no rpoB mutations were found in strains with rifampicin MICs of >2 mg/L. This study identified B. melitensis as the etiological agent of brucellosis in Qatar. No resistant isolates were detected among conventionally used antimicrobial agents. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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France | 1 | 2% |
Unknown | 47 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 19% |
Student > Ph. D. Student | 6 | 13% |
Student > Doctoral Student | 4 | 8% |
Other | 4 | 8% |
Student > Postgraduate | 4 | 8% |
Other | 9 | 19% |
Unknown | 12 | 25% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 19% |
Medicine and Dentistry | 7 | 15% |
Veterinary Science and Veterinary Medicine | 4 | 8% |
Immunology and Microbiology | 4 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Other | 6 | 13% |
Unknown | 15 | 31% |