Title |
The MDCK variety pack: choosing the right strain
|
---|---|
Published in |
BMC Molecular and Cell Biology, October 2011
|
DOI | 10.1186/1471-2121-12-43 |
Pubmed ID | |
Authors |
Joseph D Dukes, Paul Whitley, Andrew D Chalmers |
Abstract |
The MDCK cell line provides a tractable model for studying protein trafficking, polarity and junctions (tight, adherens, desmosome and gap) in epithelial cells. However, there are many different strains of MDCK cells available, including the parental line, MDCK I, MDCK II, MDCK.1, MDCK.2, superdome and supertube, making it difficult for new researchers to decide which strain to use. Furthermore, there is often inadequate reporting of strain types and where cells were obtained from in the literature. This review aims to provide new researchers with a guide to the different MDCK strains and a directory of where they can be obtained. We also hope to encourage experienced researchers to report the stain and origin of their MDCK cells. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
United Kingdom | 2 | 29% |
Austria | 1 | 14% |
Switzerland | 1 | 14% |
Unknown | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 43% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Scientists | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 3 | <1% |
United States | 3 | <1% |
United Kingdom | 2 | <1% |
Switzerland | 1 | <1% |
Belgium | 1 | <1% |
Norway | 1 | <1% |
Nigeria | 1 | <1% |
Poland | 1 | <1% |
Unknown | 393 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 97 | 24% |
Student > Bachelor | 59 | 15% |
Researcher | 58 | 14% |
Student > Master | 40 | 10% |
Student > Doctoral Student | 27 | 7% |
Other | 35 | 9% |
Unknown | 90 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 125 | 31% |
Biochemistry, Genetics and Molecular Biology | 82 | 20% |
Medicine and Dentistry | 23 | 6% |
Engineering | 19 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 15 | 4% |
Other | 47 | 12% |
Unknown | 95 | 23% |