Title |
Insulin: a wonder drug in the critically ill?
|
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Published in |
Critical Care, February 2002
|
DOI | 10.1186/cc1463 |
Pubmed ID | |
Authors |
AB Johan Groeneveld, Albertus Beishuizen, Frans C Visser |
Abstract |
Stress hyperglycaemia is a common event in acute critical illness. There is increasing evidence that maintaining normoglycaemia and treatment with insulin (or with glucose-insulin-potassium [GIK]), even in non-diabetic persons, is helpful in limiting organ damage after myocardial infarction, stroke, traumatic brain injury and other conditions, even though the conditions may be accompanied by insulin resistance. A landmark study now suggests that maintaining normoglycaemia with intensive insulin treatment in a heterogeneous population of critically ill patients decreases morbidity and mortality. The potential mechanisms that underlie such a beneficial effect are discussed. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 4% |
Unknown | 22 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 5 | 22% |
Student > Master | 5 | 22% |
Researcher | 3 | 13% |
Other | 2 | 9% |
Professor | 2 | 9% |
Other | 2 | 9% |
Unknown | 4 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 57% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
Engineering | 2 | 9% |
Business, Management and Accounting | 1 | 4% |
Unknown | 5 | 22% |