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Concept and design of a nationwide prospective feasibility/efficacy/safety study of weekly paclitaxel for patients with pathologically confirmed anaplastic thyroid cancer (ATCCJ-PTX-P2)

Overview of attention for article published in BMC Cancer, June 2015
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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Title
Concept and design of a nationwide prospective feasibility/efficacy/safety study of weekly paclitaxel for patients with pathologically confirmed anaplastic thyroid cancer (ATCCJ-PTX-P2)
Published in
BMC Cancer, June 2015
DOI 10.1186/s12885-015-1490-8
Pubmed ID
Authors

Naoyoshi Onoda, Iwao Sugitani, Takuya Higashiyama, Hisato Hara, Ken-ichi Ito, Makoto Kammori, Kiminori Sugino, Shinichi Suzuki, Kazuhisa Toda, Akira Yoshida, Akira Miyauchi

Abstract

Anaplastic thyroid cancer (ATC) is one of the most aggressive malignancies in humans, often demonstrating resistance to multimodal therapeutic approaches. The median survival of ATC patients after initial diagnosis was reported to be < 6 months due to the rapid progression of disease by dissemination and/or invasion. There have been several reports describing possible effective chemotherapies, but these studies might be biased by the nature of retrospective accumulations of clinical experiences, and thus reliable data concerning the efficacies of the treatment efforts are required. In 2009, we established the research organization Anaplastic Carcinoma Research Consortium Japan (ATCCJ) to investigate this highly malignant disease. Using this nationwide organization, we conducted a prospective clinical study to investigate the feasibility, safeness, and efficacy of chemotherapy with weekly paclitaxel for ATC patients. This trial is registered on the clinical trials site of the University Hospital Medical Information Network Clinical Trials Registry Web site (UMIN000008574). The study was started in 2012, and enrollment was closed in March 2014 after accumulating 71 patients from 28 registered institutes. The follow-up data will be available in April 2015. Important information concerning the management of this disease is expected to be revealed by this study. The concept and design of the study are described herein.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 13%
Professor 3 13%
Researcher 3 13%
Lecturer 2 8%
Student > Ph. D. Student 2 8%
Other 4 17%
Unknown 7 29%
Readers by discipline Count As %
Medicine and Dentistry 7 29%
Nursing and Health Professions 2 8%
Agricultural and Biological Sciences 2 8%
Arts and Humanities 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 2 8%
Unknown 9 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2019.
All research outputs
#13,440,185
of 22,813,792 outputs
Outputs from BMC Cancer
#2,973
of 8,299 outputs
Outputs of similar age
#124,284
of 264,425 outputs
Outputs of similar age from BMC Cancer
#65
of 193 outputs
Altmetric has tracked 22,813,792 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,299 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,425 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 193 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.