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Impact of antigenic and genetic drift on the serologic surveillance of H5N2 avian influenza viruses

Overview of attention for article published in BMC Veterinary Research, December 2010
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Title
Impact of antigenic and genetic drift on the serologic surveillance of H5N2 avian influenza viruses
Published in
BMC Veterinary Research, December 2010
DOI 10.1186/1746-6148-6-57
Pubmed ID
Authors

Magdalena Escorcia, Karol Carrillo-Sánchez, Santiago March-Mifsut, Joaquin Chapa, Eduardo Lucio, Gerardo M Nava

Abstract

Serologic surveillance of Avian Influenza (AI) viruses is carried out by the hemagglutination inhibition (HI) test using reference reagents. This method is recommended by animal health organizations as a standard test to detect antigenic differences (subtypes) between circulating influenza virus, vaccine- and/or reference- strains. However, significant discrepancies between reference antisera and field isolates have been observed during serosurveillance of influenza A viruses in pig and poultry farms. The objective of this study was to examine the effects of influenza virus genetic and antigenic drift on serologic testing using standard HI assays and reference reagents. Low pathogenic AI H5N2 viruses isolated in Mexico between 1994 and 2008 were used for phylogenetic analysis of AI hemagglutinin genes and for serologic testing using antisera produced with year-specific AI virus isolates.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
Italy 1 2%
United Kingdom 1 2%
Mexico 1 2%
Denmark 1 2%
Unknown 39 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 18%
Unspecified 7 16%
Student > Master 6 14%
Researcher 5 11%
Professor 3 7%
Other 5 11%
Unknown 10 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 23%
Unspecified 7 16%
Veterinary Science and Veterinary Medicine 4 9%
Medicine and Dentistry 4 9%
Immunology and Microbiology 3 7%
Other 6 14%
Unknown 10 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2011.
All research outputs
#15,237,301
of 22,655,397 outputs
Outputs from BMC Veterinary Research
#1,411
of 3,031 outputs
Outputs of similar age
#141,505
of 181,832 outputs
Outputs of similar age from BMC Veterinary Research
#16
of 20 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,031 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 181,832 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.