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Prevalence of methicillin-resistant Staphylococcus aureus colonization in HIV-infected patients in Barcelona, Spain: a cross-sectional study

Overview of attention for article published in BMC Infectious Diseases, June 2015
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Title
Prevalence of methicillin-resistant Staphylococcus aureus colonization in HIV-infected patients in Barcelona, Spain: a cross-sectional study
Published in
BMC Infectious Diseases, June 2015
DOI 10.1186/s12879-015-0991-z
Pubmed ID
Authors

Arkaitz Imaz, Mariana Camoez, Silvana Di Yacovo, Oriol Gasch, M Angeles Dominguez, Antonia Vila, Margarita Maso-Serra, Miquel Pujol, Daniel Podzamczer

Abstract

Colonization by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been found to be markedly more common in HIV-infected individuals in the USA. Studies evaluating the prevalence MRSA colonization in HIV-infected populations in Europe are scarce. The aim of this study was to investigate the prevalence of MRSA colonization in a cohort of HIV-infected patients in Barcelona, Spain. Nasal and pharyngeal S. aureus carriage was assessed in a random sample of 190 patients from an outpatient HIV clinic. Nasal and pharyngeal swab specimens were obtained for staphylococcal culture from 190 and 110 patients respectively. All MRSA isolates were screened for Panton-Valentine leukocidin (PVL) genes by PCR. Molecular characterization of MRSA isolates was performed by multilocus sequence typing. Data related to HIV infection, healthcare exposure, and previously described risk factors for MRSA were collected from medical records and a questionnaire administered to each patient. The patients' characteristics were as follows: male, 83 %; median (IQR) age, 45 (39-49) years; intravenous drug users, 39 %; men who have sex with men, 32 %; heterosexual, 26 %; CD4 count, 528/μL (IQR 351-740); on antiretroviral therapy, 96 %; and undetectable plasma viral load, 80 %. Sixty-five patients (34 %) were colonized by S. aureus. MRSA colonization was found in 1 % and 2 % of nasal and pharyngeal samples respectively. No PVL positive MRSA strains were detected and all the MRSA isolates belonged to typical hospital-acquired clones. Our data suggest that CA-MRSA colonization is not currently a problem in HIV-infected individuals in our area.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 2%
Unknown 58 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 15%
Researcher 7 12%
Student > Bachelor 6 10%
Student > Doctoral Student 5 8%
Other 5 8%
Other 9 15%
Unknown 18 31%
Readers by discipline Count As %
Medicine and Dentistry 19 32%
Biochemistry, Genetics and Molecular Biology 4 7%
Agricultural and Biological Sciences 4 7%
Immunology and Microbiology 3 5%
Nursing and Health Professions 2 3%
Other 7 12%
Unknown 20 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2015.
All research outputs
#17,764,580
of 22,815,414 outputs
Outputs from BMC Infectious Diseases
#5,103
of 7,675 outputs
Outputs of similar age
#176,911
of 263,581 outputs
Outputs of similar age from BMC Infectious Diseases
#70
of 107 outputs
Altmetric has tracked 22,815,414 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,675 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,581 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.