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Chemopreventive effect of cactus Opuntia ficus indica on oxidative stress and genotoxicity of aflatoxin B1

Overview of attention for article published in Nutrition & Metabolism, October 2011
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

Mentioned by

policy
1 policy source
twitter
1 X user
facebook
3 Facebook pages

Citations

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67 Dimensions

Readers on

mendeley
69 Mendeley
citeulike
1 CiteULike
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Title
Chemopreventive effect of cactus Opuntia ficus indica on oxidative stress and genotoxicity of aflatoxin B1
Published in
Nutrition & Metabolism, October 2011
DOI 10.1186/1743-7075-8-73
Pubmed ID
Authors

Dalel Brahmi, Chayma Bouaziz, Yousra Ayed, Hédi Ben Mansour, Lazhar Zourgui, Hassen Bacha

Abstract

Aflatoxin B1 (AFB1) is potent hepatotoxic and hepatocarcinogenic agent. In aflatoxicosis, oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage. The aim of this work was to evaluate the hepatoprotective effect of cactus cladode extract (CCE) on aflatoxin B1-induced liver damage in mice by measuring malondialdehyde (MDA) level, the protein carbonyls generation and the heat shock proteins Hsp 70 and Hsp 27 expressions in liver. We also looked for an eventual protective effect against AFB1-induced genotoxicity as determined by chromosome aberrations test, SOS Chromotest and DNA fragmentation assay. We further evaluated the modulation of p53, bax and bcl2 protein expressions in liver.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 68 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 19%
Researcher 9 13%
Unspecified 7 10%
Student > Master 7 10%
Student > Doctoral Student 6 9%
Other 19 28%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 25%
Pharmacology, Toxicology and Pharmaceutical Science 8 12%
Medicine and Dentistry 7 10%
Unspecified 7 10%
Chemistry 5 7%
Other 14 20%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2018.
All research outputs
#6,001,861
of 22,655,397 outputs
Outputs from Nutrition & Metabolism
#411
of 942 outputs
Outputs of similar age
#36,619
of 139,128 outputs
Outputs of similar age from Nutrition & Metabolism
#5
of 11 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 942 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.3. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 139,128 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.