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Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis

Overview of attention for article published in BMC Medical Genomics, May 2018
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Title
Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis
Published in
BMC Medical Genomics, May 2018
DOI 10.1186/s12881-018-0604-y
Pubmed ID
Authors

Yong-Hui Chen, Ying-Qiang Zhang

Abstract

Several association analyses and linkage researches indicated that inherited genetic variations effectively influence differentiated thyroid carcinogenesis. The results from 15 published studies on differentiated thyroid carcinoma (DTC) were combined. The genetic model included rs965513, rs944289 and rs1867277. Meta-analyses were performed and cochran's χ2 based Q-statistic and I2 test were performed to assess heterogeneity using STATA software. Significant results were noticed for rs965513(Odds Ratio(OR) = 1.162(1.117, 1.208)), rs944289(OR = 1.082(1.035, 1.131)) and rs1867277(OR = 1.415(1.324, 1.512)). In the subgroup analysis by ethnicity, rs965513 polymorphism conferred that risk of Caucasians (OR = 1.168(1.122, 1.215)) was more than that of East Asians of 1.35 (OR = 0.897(0.680, 1.193)). This meta-analysis revealed that common variations of FOXE1 (rs965513, rs944289 and rs1867277) were risk factors associated with increased DTC susceptibility.

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Mendeley readers

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The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 21%
Student > Ph. D. Student 3 16%
Student > Doctoral Student 1 5%
Student > Bachelor 1 5%
Professor 1 5%
Other 2 11%
Unknown 7 37%
Readers by discipline Count As %
Medicine and Dentistry 6 32%
Biochemistry, Genetics and Molecular Biology 2 11%
Agricultural and Biological Sciences 1 5%
Computer Science 1 5%
Unknown 9 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2018.
All research outputs
#22,767,715
of 25,382,440 outputs
Outputs from BMC Medical Genomics
#2,010
of 2,444 outputs
Outputs of similar age
#302,081
of 343,970 outputs
Outputs of similar age from BMC Medical Genomics
#41
of 55 outputs
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