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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
|
|---|---|
| Published in |
BMC Cancer, October 2011
|
| DOI | 10.1186/1471-2407-11-455 |
| Pubmed ID | |
| Authors |
Geir Olav Hjortland, Leonardo A Meza-Zepeda, Klaus Beiske, Anne H Ree, Siri Tveito, Hanne Hoifodt, Per J Bohler, Knut H Hole, Ola Myklebost, Oystein Fodstad, Sigbjorn Smeland, Eivind Hovig |
| Abstract |
Metastatic progression due to development or enrichment of therapy-resistant tumor cells is eventually lethal. Molecular characterization of such chemotherapy resistant tumor cell clones may identify markers responsible for malignant progression and potential targets for new treatment. Here, in a case of stage IV adenocarcinoma of the gastroesophageal junction, we report the successful genome wide analysis using array comparative genomic hybridization (CGH) of DNA from only fourteen tumor cells using a bead-based single cell selection method from a bone metastasis progressing during chemotherapy. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 2% |
| Unknown | 50 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 14% |
| Student > Bachelor | 7 | 14% |
| Other | 6 | 12% |
| Student > Master | 6 | 12% |
| Professor | 4 | 8% |
| Other | 12 | 24% |
| Unknown | 9 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 41% |
| Biochemistry, Genetics and Molecular Biology | 7 | 14% |
| Agricultural and Biological Sciences | 6 | 12% |
| Nursing and Health Professions | 3 | 6% |
| Environmental Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 11 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2011.
All research outputs
#13,356,164
of 22,655,397 outputs
Outputs from BMC Cancer
#2,963
of 8,237 outputs
Outputs of similar age
#85,514
of 139,451 outputs
Outputs of similar age from BMC Cancer
#38
of 93 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,237 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 139,451 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.