Title |
High-throughput sequencing of Astrammina rara: Sampling the giant genome of a giant foraminiferan protist
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Published in |
BMC Genomics, March 2011
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DOI | 10.1186/1471-2164-12-169 |
Pubmed ID | |
Authors |
Andrea Habura, Yubo Hou, Andrew A Reilly, Samuel S Bowser |
Abstract |
Foraminiferan protists, which are significant players in most marine ecosystems, are also genetic innovators, harboring unique modifications to proteins that make up the basic eukaryotic cell machinery. Despite their ecological and evolutionary importance, foraminiferan genomes are poorly understood due to the extreme sequence divergence of many genes and the difficulty of obtaining pure samples: exogenous DNA from ingested food or ecto/endo symbionts often vastly exceed the amount of "native" DNA, and foraminiferans cannot be cultured axenically. Few foraminiferal genes have been sequenced from genomic material, although partial sequences of coding regions have been determined by EST studies and mass spectroscopy. The lack of genomic data has impeded evolutionary and cell-biology studies and has also hindered our ability to test ecological hypotheses using genetic tools. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Canada | 2 | 3% |
Norway | 2 | 3% |
United Kingdom | 1 | 1% |
Unknown | 67 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 22 | 31% |
Student > Ph. D. Student | 15 | 21% |
Professor > Associate Professor | 5 | 7% |
Professor | 4 | 6% |
Student > Doctoral Student | 4 | 6% |
Other | 12 | 17% |
Unknown | 10 | 14% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 32 | 44% |
Biochemistry, Genetics and Molecular Biology | 14 | 19% |
Environmental Science | 4 | 6% |
Earth and Planetary Sciences | 4 | 6% |
Business, Management and Accounting | 1 | 1% |
Other | 3 | 4% |
Unknown | 14 | 19% |