Title |
Acute lung injury: how to stabilize a broken lung
|
---|---|
Published in |
Critical Care, May 2018
|
DOI | 10.1186/s13054-018-2051-8 |
Pubmed ID | |
Authors |
Gary F. Nieman, Penny Andrews, Joshua Satalin, Kailyn Wilcox, Michaela Kollisch-Singule, Maria Madden, Hani Aiash, Sarah J. Blair, Louis A. Gatto, Nader M. Habashi |
Abstract |
The pathophysiology of acute respiratory distress syndrome (ARDS) results in heterogeneous lung collapse, edema-flooded airways and unstable alveoli. These pathologic alterations in alveolar mechanics (i.e. dynamic change in alveolar size and shape with each breath) predispose the lung to secondary ventilator-induced lung injury (VILI). It is our viewpoint that the acutely injured lung can be recruited and stabilized with a mechanical breath until it heals, much like casting a broken bone until it mends. If the lung can be "casted" with a mechanical breath, VILI could be prevented and ARDS incidence significantly reduced. |
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Netherlands | 3 | 2% |
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Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 13 | 11% |
Scientists | 11 | 9% |
Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
Geographical breakdown
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Unknown | 184 | 100% |
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Researcher | 31 | 17% |
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Student > Ph. D. Student | 14 | 8% |
Student > Postgraduate | 14 | 8% |
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Unknown | 27 | 15% |
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