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The cerebrospinal fluid biomarker profile in an HIV-infected subject with Alzheimer’s disease

Overview of attention for article published in AIDS Research and Therapy, July 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user

Citations

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17 Dimensions

Readers on

mendeley
37 Mendeley
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Title
The cerebrospinal fluid biomarker profile in an HIV-infected subject with Alzheimer’s disease
Published in
AIDS Research and Therapy, July 2015
DOI 10.1186/s12981-015-0063-x
Pubmed ID
Authors

Signar Mäkitalo, Åsa Mellgren, Ellen Borgh, Lena Kilander, Tobias Skillbäck, Henrik Zetterberg, Magnus Gisslén

Abstract

It is a challenge to differentiate between HIV-associated neurocognitive disorders (HAND) and other types of neurocognitive disease in the ageing HIV-infected population. Here we describe a 63 year old HIV-infected woman who had a history, neuropsychological test result, and PET examination consistent with characteristic Alzheimer's disease (AD). The cerebrospinal fluid (CSF) biomarker profile was analogous to the profile typically found in AD in HIV-negative patients with increased t-tau and p-tau, a decreased level of Aβ42 and normal levels of CSF neurofilament light protein and sAPPα and sAPPβ, distinctly different from findings in HIV-associated dementia (HAD). Assessment of CSF biomarkers may be a valuable tool for clinicians to distinguish between HAD and AD.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
Unknown 35 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 19%
Student > Ph. D. Student 6 16%
Researcher 5 14%
Student > Bachelor 3 8%
Student > Postgraduate 3 8%
Other 4 11%
Unknown 9 24%
Readers by discipline Count As %
Medicine and Dentistry 12 32%
Neuroscience 5 14%
Agricultural and Biological Sciences 2 5%
Psychology 2 5%
Nursing and Health Professions 1 3%
Other 5 14%
Unknown 10 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2015.
All research outputs
#2,941,235
of 22,816,807 outputs
Outputs from AIDS Research and Therapy
#59
of 551 outputs
Outputs of similar age
#39,433
of 262,658 outputs
Outputs of similar age from AIDS Research and Therapy
#3
of 9 outputs
Altmetric has tracked 22,816,807 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 551 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,658 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.