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Risk of psychiatric disorders following trigeminal neuralgia: a nationwide population-based retrospective cohort study

Overview of attention for article published in The Journal of Headache and Pain, July 2015
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Title
Risk of psychiatric disorders following trigeminal neuralgia: a nationwide population-based retrospective cohort study
Published in
The Journal of Headache and Pain, July 2015
DOI 10.1186/s10194-015-0548-y
Pubmed ID
Authors

Tung-Han Wu, Li-Yu Hu, Ti Lu, Pan-Ming Chen, Hon-Jhe Chen, Cheng-Che Shen, Chun-Hsien Wen

Abstract

TN is one of the most common causes of facial pain. A higher prevalence of psychiatric co-morbidities, especially depressive disorder, has been proven in patients with TN; however, a clear temporal-causal relationship between TN and specific psychiatric disorders has not been well established. We performed a nationwide population-based retrospective cohort study to explore the relationship between TN and the subsequent development of psychiatric disorders, including schizophrenia, bipolar disorder, depressive disorder, anxiety disorder, and sleep disorder. We identified subjects who were newly diagnosed with TN between January 1, 2000 and December 31, 2010 in the Taiwan National Health Insurance Research Database. A comparison cohort was constructed for patients without TN who were matched according to age and sex. All TN and control patients were observed until diagnosed with psychiatric disorders, death, withdrawal from the National Health Institute system, or until December 31, 2010. The TN cohort consisted of 3273 patients, and the comparison cohort consisted of 13,092 matched control patients without TN. The adjusted hazard ratio (aHR) of depressive disorder, anxiety disorder and sleep disorder in subjects with TN was higher than that of the controls during the follow-up [aHR: 2.85 (95 % confidence interval: 2.11-3.85), aHR: 2.98 (95 % confidence interval: 2.12-4.18) and aHR: 2.17 (95 % confidence interval: 1.48-3.19), respectively]. TN might increase the risk of subsequent newly diagnosed depressive disorder, anxiety disorder, and sleep disorder, but not schizophrenia or bipolar disorder. Additional prospective studies are required to confirm these findings.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 123 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 21 17%
Student > Master 15 12%
Researcher 11 9%
Student > Ph. D. Student 11 9%
Other 8 7%
Other 15 12%
Unknown 42 34%
Readers by discipline Count As %
Medicine and Dentistry 40 33%
Psychology 13 11%
Nursing and Health Professions 6 5%
Neuroscience 5 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 11 9%
Unknown 45 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2015.
All research outputs
#19,244,099
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#1,210
of 1,417 outputs
Outputs of similar age
#191,667
of 264,698 outputs
Outputs of similar age from The Journal of Headache and Pain
#20
of 23 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
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