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SUVmax of 18F-FDG PET/CT in the differential diagnosis of benign and malignant thyroid nodules according to tumor volume

Overview of attention for article published in World Journal of Surgical Oncology, July 2015
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Title
SUVmax of 18F-FDG PET/CT in the differential diagnosis of benign and malignant thyroid nodules according to tumor volume
Published in
World Journal of Surgical Oncology, July 2015
DOI 10.1186/s12957-015-0635-1
Pubmed ID
Authors

Tae Heon Kim, Yong Bae Ji, Chang Myeon Song, Ji Young Kim, Yun Young Choi, Jeong Seon Park, Kyung Tae

Abstract

The aim of this study was to investigate whether the maximum standardized uptake value (SUVmax) measured on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) could be used as the primary means of differential diagnosis of thyroid nodules when tumor volume is assessed. We studied 192 patients who underwent preoperative (18)F-FDG PET/CT followed by thyroidectomy. We evaluated the correlation between the volume of thyroid nodules, (18)F-FDG uptake on visual analysis, and the mean SUVmax measured on (18)F-FDG PET/CT. When stratified by tumor volume, the mean SUVmax was higher in malignant than in benign nodules in nodules ≥1 cm(3) (p < 0.001). However, it did not differ between benign and malignant nodules smaller than 1 cm(3). At a cut-off value of SUVmax of 6, the respective sensitivities of (18)F-FDG PET/CT, ultrasonography, and fine needle aspiration cytology were 60.8, 96.4, and 99.1 %, and the respective specificities were 95.9, 98.2, and 96.8 %. (18)F-FDG PET/CT is limited as a primary modality in the differential diagnosis of benign and malignant thyroid nodules because of its low sensitivity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 19%
Student > Ph. D. Student 3 19%
Student > Master 2 13%
Professor 2 13%
Other 1 6%
Other 2 13%
Unknown 3 19%
Readers by discipline Count As %
Medicine and Dentistry 6 38%
Nursing and Health Professions 2 13%
Neuroscience 2 13%
Biochemistry, Genetics and Molecular Biology 1 6%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2016.
All research outputs
#17,178,028
of 25,233,554 outputs
Outputs from World Journal of Surgical Oncology
#663
of 2,139 outputs
Outputs of similar age
#160,527
of 268,635 outputs
Outputs of similar age from World Journal of Surgical Oncology
#17
of 50 outputs
Altmetric has tracked 25,233,554 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,139 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,635 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.