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Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice

Overview of attention for article published in Gut Pathogens, January 2011
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (57th percentile)

Mentioned by

twitter
3 tweeters

Citations

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23 Dimensions

Readers on

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54 Mendeley
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Title
Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice
Published in
Gut Pathogens, January 2011
DOI 10.1186/1757-4749-3-16
Pubmed ID
Authors

Leo R Fitzpatrick, Jeffrey S Small, Wallace H Greene, Kelly D Karpa, David Keller

Abstract

Probiotics have beneficial effects in rodent models of Clostridium difficile (C. diffiicle)-induced colitis. The spore forming probiotic strain Bacillus Coagulans GBI-30, 6086 (BC30) has demonstrated anti-inflammatory and immune-modulating effects in vitro. Our goal was to determine if BC30 improved C. difficile-induced colitis in mice. Starting on study day 0, female C57BL/6 mice were dosed by oro-gastric gavage for 15 days with vehicle (saline) or BC30 (2 × 109 CFU per day). Mice in the C. difficile groups received an antibiotic mixture (study days 5 to 8 in the drinking water), and clindamycin (10 mg/kg, i.p., on study day 10). The C. difficile strain VPI 10463 was given by gavage at 104 CFU to induce colitis on day 11. On day 16, stools and colons were collected for further analyses.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Italy 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Researcher 9 17%
Student > Master 8 15%
Student > Bachelor 6 11%
Student > Postgraduate 3 6%
Other 7 13%
Unknown 11 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 33%
Medicine and Dentistry 10 19%
Chemistry 3 6%
Immunology and Microbiology 3 6%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 5 9%
Unknown 13 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2012.
All research outputs
#3,049,680
of 11,222,141 outputs
Outputs from Gut Pathogens
#73
of 256 outputs
Outputs of similar age
#26,761
of 98,865 outputs
Outputs of similar age from Gut Pathogens
#2
of 3 outputs
Altmetric has tracked 11,222,141 research outputs across all sources so far. This one has received more attention than most of these and is in the 50th percentile.
So far Altmetric has tracked 256 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,865 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.