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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Can sustained arousal explain the Chronic Fatigue Syndrome?
|
|---|---|
| Published in |
Behavioral and Brain Functions, February 2009
|
| DOI | 10.1186/1744-9081-5-10 |
| Pubmed ID | |
| Authors |
Vegard B Wyller, Hege R Eriksen, Kirsti Malterud |
| Abstract |
We present an integrative model of disease mechanisms in the Chronic Fatigue Syndrome (CFS), unifying empirical findings from different research traditions. Based upon the Cognitive activation theory of stress (CATS), we argue that new data on cardiovascular and thermoregulatory regulation indicate a state of permanent arousal responses - sustained arousal - in this condition. We suggest that sustained arousal can originate from different precipitating factors (infections, psychosocial challenges) interacting with predisposing factors (genetic traits, personality) and learned expectancies (classical and operant conditioning). Furthermore, sustained arousal may explain documented alterations by establishing vicious circles within immunology (Th2 (humoral) vs Th1 (cellular) predominance), endocrinology (attenuated HPA axis), skeletal muscle function (attenuated cortical activation, increased oxidative stress) and cognition (impaired memory and information processing). Finally, we propose a causal link between sustained arousal and the experience of fatigue. The model of sustained arousal embraces all main findings concerning CFS disease mechanisms within one theoretical framework. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 15% |
| Norway | 2 | 15% |
| Unknown | 9 | 69% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 62% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
| Scientists | 1 | 8% |
| Unknown | 3 | 23% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 2% |
| New Zealand | 1 | 1% |
| Norway | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 79 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 23% |
| Researcher | 16 | 19% |
| Student > Ph. D. Student | 12 | 14% |
| Student > Bachelor | 8 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Other | 15 | 18% |
| Unknown | 7 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 23 | 27% |
| Medicine and Dentistry | 17 | 20% |
| Neuroscience | 6 | 7% |
| Agricultural and Biological Sciences | 5 | 6% |
| Nursing and Health Professions | 5 | 6% |
| Other | 19 | 23% |
| Unknown | 9 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2024.
All research outputs
#3,689,213
of 25,374,917 outputs
Outputs from Behavioral and Brain Functions
#77
of 417 outputs
Outputs of similar age
#12,718
of 109,795 outputs
Outputs of similar age from Behavioral and Brain Functions
#5
of 11 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,795 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.