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1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier

Overview of attention for article published in Fluids and Barriers of the CNS, July 2011
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3 X users
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2 Facebook pages

Citations

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86 Dimensions

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73 Mendeley
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Title
1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier
Published in
Fluids and Barriers of the CNS, July 2011
DOI 10.1186/2045-8118-8-20
Pubmed ID
Authors

Shingo Ito, Sumio Ohtsuki, Yasuko Nezu, Yusuke Koitabashi, Sho Murata, Tetsuya Terasaki

Abstract

Cerebrovascular dysfunction has been considered to cause impairment of cerebral amyloid-β peptide (Aβ) clearance across the blood-brain barrier (BBB). Further, low levels of vitamin D are associated with increased risk of Alzheimer's disease, as well as vascular dysfunction. The purpose of the present study was to investigate the effect of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), an active form of vitamin D, on cerebral Aβ clearance from mouse brain.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 72 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 15%
Student > Doctoral Student 10 14%
Researcher 7 10%
Student > Master 7 10%
Student > Bachelor 6 8%
Other 13 18%
Unknown 19 26%
Readers by discipline Count As %
Medicine and Dentistry 20 27%
Agricultural and Biological Sciences 14 19%
Biochemistry, Genetics and Molecular Biology 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Nursing and Health Professions 2 3%
Other 7 10%
Unknown 22 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2013.
All research outputs
#14,600,553
of 25,374,647 outputs
Outputs from Fluids and Barriers of the CNS
#226
of 496 outputs
Outputs of similar age
#84,468
of 127,802 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#2
of 2 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 496 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,802 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.