↓ Skip to main content

Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects

Overview of attention for article published in Respiratory Research, December 2011
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

twitter
7 X users
facebook
1 Facebook page

Citations

dimensions_citation
80 Dimensions

Readers on

mendeley
53 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
Published in
Respiratory Research, December 2011
DOI 10.1186/1465-9921-12-140
Pubmed ID
Authors

Gail M Gauvreau, Louis-Philippe Boulet, Christine Schmid-Wirlitsch, Johanne Côté, MyLinh Duong, Kieran J Killian, Joanne Milot, Francine Deschesnes, Tara Strinich, Richard M Watson, Dirk Bredenbröker, Paul M O'Byrne

Abstract

Phosphodiesterase 4 (PDE4) inhibitors increase intracellular cyclic adenosine monophosphate (cAMP), leading to regulation of inflammatory cell functions. Roflumilast is a potent and targeted PDE4 inhibitor. The objective of this study was to evaluate the effects of roflumilast on bronchoconstriction, airway hyperresponsiveness (AHR), and airway inflammation in mild asthmatic patients undergoing allergen inhalation challenge.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Canada 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 13%
Student > Ph. D. Student 6 11%
Other 5 9%
Professor > Associate Professor 5 9%
Student > Doctoral Student 5 9%
Other 15 28%
Unknown 10 19%
Readers by discipline Count As %
Medicine and Dentistry 20 38%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Agricultural and Biological Sciences 5 9%
Biochemistry, Genetics and Molecular Biology 4 8%
Engineering 2 4%
Other 4 8%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2012.
All research outputs
#5,204,873
of 25,373,627 outputs
Outputs from Respiratory Research
#646
of 3,062 outputs
Outputs of similar age
#40,203
of 246,216 outputs
Outputs of similar age from Respiratory Research
#17
of 69 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,216 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.