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The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany

Overview of attention for article published in BMC Public Health, July 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
4 X users
facebook
1 Facebook page

Citations

dimensions_citation
274 Dimensions

Readers on

mendeley
284 Mendeley
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1 CiteULike
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Title
The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany
Published in
BMC Public Health, July 2015
DOI 10.1186/s12889-015-1983-z
Pubmed ID
Authors

Markus Loeffler, Christoph Engel, Peter Ahnert, Dorothee Alfermann, Katrin Arelin, Ronny Baber, Frank Beutner, Hans Binder, Elmar Brähler, Ralph Burkhardt, Uta Ceglarek, Cornelia Enzenbach, Michael Fuchs, Heide Glaesmer, Friederike Girlich, Andreas Hagendorff, Madlen Häntzsch, Ulrich Hegerl, Sylvia Henger, Tilman Hensch, Andreas Hinz, Volker Holzendorf, Daniela Husser, Anette Kersting, Alexander Kiel, Toralf Kirsten, Jürgen Kratzsch, Knut Krohn, Tobias Luck, Susanne Melzer, Jeffrey Netto, Matthias Nüchter, Matthias Raschpichler, Franziska G. Rauscher, Steffi G. Riedel-Heller, Christian Sander, Markus Scholz, Peter Schönknecht, Matthias L. Schroeter, Jan-Christoph Simon, Ronald Speer, Julia Stäker, Robert Stein, Yve Stöbel-Richter, Michael Stumvoll, Attila Tarnok, Andrej Teren, Daniel Teupser, Francisca S. Then, Anke Tönjes, Regina Treudler, Arno Villringer, Alexander Weissgerber, Peter Wiedemann, Silke Zachariae, Kerstin Wirkner, Joachim Thiery

Abstract

The LIFE-Adult-Study is a population-based cohort study, which has recently completed the baseline examination of 10,000 randomly selected participants from Leipzig, a major city with 550,000 inhabitants in the east of Germany. It is the first study of this kind and size in an urban population in the eastern part of Germany. The study is conducted by the Leipzig Research Centre for Civilization Diseases (LIFE). Our objective is to investigate prevalences, early onset markers, genetic predispositions, and the role of lifestyle factors of major civilization diseases, with primary focus on metabolic and vascular diseases, heart function, cognitive impairment, brain function, depression, sleep disorders and vigilance dysregulation, retinal and optic nerve degeneration, and allergies. The study covers a main age range from 40-79 years with particular deep phenotyping in elderly participants above the age of 60. The baseline examination was conducted from August 2011 to November 2014. All participants underwent an extensive core assessment programme (5-6 h) including structured interviews, questionnaires, physical examinations, and biospecimen collection. Participants over 60 underwent two additional assessment programmes (3-4 h each) on two separate visits including deeper cognitive testing, brain magnetic resonance imaging, diagnostic interviews for depression, and electroencephalography. The participation rate was 33 %. The assessment programme was accepted well and completely passed by almost all participants. Biomarker analyses have already been performed in all participants. Genotype, transcriptome and metabolome analyses have been conducted in subgroups. The first follow-up examination will commence in 2016.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 284 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 1%
Australia 1 <1%
Switzerland 1 <1%
Brazil 1 <1%
Unknown 278 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 44 15%
Student > Master 35 12%
Student > Doctoral Student 29 10%
Student > Ph. D. Student 28 10%
Student > Bachelor 25 9%
Other 38 13%
Unknown 85 30%
Readers by discipline Count As %
Medicine and Dentistry 54 19%
Psychology 23 8%
Neuroscience 21 7%
Biochemistry, Genetics and Molecular Biology 17 6%
Agricultural and Biological Sciences 16 6%
Other 53 19%
Unknown 100 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 September 2023.
All research outputs
#2,057,983
of 25,837,817 outputs
Outputs from BMC Public Health
#2,445
of 17,839 outputs
Outputs of similar age
#25,335
of 278,661 outputs
Outputs of similar age from BMC Public Health
#34
of 282 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,839 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,661 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 282 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.