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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Immunotherapeutic interventions of Triple Negative Breast Cancer
|
|---|---|
| Published in |
Journal of Translational Medicine, May 2018
|
| DOI | 10.1186/s12967-018-1514-7 |
| Pubmed ID | |
| Authors |
Zehuan Li, Yiran Qiu, Weiqi Lu, Ying Jiang, Jin Wang |
| Abstract |
Triple Negative Breast Cancer (TNBC) is a highly heterogeneous subtype of breast cancer that lacks the expression of oestrogen receptors, progesterone receptors and human epidermal growth factor receptor 2. Although TNBC is sensitive to chemotherapy, the overall outcomes of TNBC are worse than for other breast cancers, and TNBC is still one of the most fatal diseases for women. With the discovery of antigens specifically expressed in TNBC cells and the developing technology of monoclonal antibodies, chimeric antigen receptors and cancer vaccines, immunotherapy is emerging as a novel promising option for TNBC. This review is mainly focused on the tumour microenvironment and host immunity, Triple Negative Breast Cancer and the clinical treatment of TNBC, novel therapies for cancer and immunotherapy for TNBC, and the future outlook for the treatment for TNBC and the interplay between the therapies, including immune checkpoint inhibitors, combination of immune checkpoint inhibitors with targeted treatments in TNBC, adoptive cell therapy, cancer vaccines. The review also highlights recent reports on the synergistic effects of immunotherapy and chemotherapy, antibody-drug conjugates, and exosomes, as potential multifunctional therapeutic agents in TNBC. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 204 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 204 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 15% |
| Student > Bachelor | 28 | 14% |
| Student > Master | 22 | 11% |
| Researcher | 20 | 10% |
| Other | 11 | 5% |
| Other | 28 | 14% |
| Unknown | 65 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 48 | 24% |
| Medicine and Dentistry | 35 | 17% |
| Agricultural and Biological Sciences | 17 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 6% |
| Immunology and Microbiology | 9 | 4% |
| Other | 16 | 8% |
| Unknown | 67 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2023.
All research outputs
#6,630,142
of 24,293,076 outputs
Outputs from Journal of Translational Medicine
#1,041
of 4,333 outputs
Outputs of similar age
#110,035
of 335,174 outputs
Outputs of similar age from Journal of Translational Medicine
#13
of 94 outputs
Altmetric has tracked 24,293,076 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 4,333 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,174 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.