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Acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue: a multicenter, nonblinded, randomized controlled trial

Overview of attention for article published in Trials, July 2015
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Title
Acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue: a multicenter, nonblinded, randomized controlled trial
Published in
Trials, July 2015
DOI 10.1186/s13063-015-0857-0
Pubmed ID
Authors

Jung-Eun Kim, Byung-Kwan Seo, Jin-Bong Choi, Hyeong-Jun Kim, Tae-Hun Kim, Min-Hee Lee, Kyung-Won Kang, Joo-Hee Kim, Kyung-Min Shin, Seunghoon Lee, So-Young Jung, Ae-Ran Kim, Mi-Suk Shin, Hee-Jung Jung, Hyo-Ju Park, Sung-Phil Kim, Yong-Hyeon Baek, Kwon-Eui Hong, Sun-Mi Choi

Abstract

The causes of chronic fatigue syndrome (CFS) and idiopathic chronic fatigue (ICF) are not clearly known, and there are no definitive treatments for them. Therefore, patients with CFS and ICF are interested in Oriental medicine or complementary and alternative medicine. For this reason, the effectiveness of complementary and alternative treatments should be verified. We investigated the effectiveness of two forms of acupuncture added to usual care for CFS and ICF compared to usual care alone. A three-arm parallel, non-blinded, randomized controlled trial was performed in four hospitals. We divided 150 participants into treatment and control groups at the same ratio. The treatment groups (Group A, body acupuncture; Group B, Sa-am acupuncture) received 10 sessions for 4 weeks. The control group (Group C) continued usual care alone. The primary outcome was the Fatigue Severity Scale (FSS) at 5 weeks after randomization. Secondary outcomes were the FSS at 13 weeks and a short form of the Stress Response Inventory (SRI), the Beck Depression Inventory (BDI), the Numeric Rating Scale (NRS), and the EuroQol-5 Dimension (EQ-5D) at 5 and 13 weeks. Group A showed significantly lower FSS scores than Group C at 5 weeks (P = 0.023). SRI scores were significantly lower in the treatment groups than in the control group at 5 (Group A, P = 0.032; B, P <0.001) and 13 weeks (Group A, P = 0.037; B, P <0.001). Group B showed significantly lower BDI scores than Group C at 13 weeks (P = 0.007). NRS scores from the treatment groups were significantly reduced compared to control at 5 (Group A and B, P <0.001) and 13 weeks (Group A, P = 0.011; B, P = 0.002). Body acupuncture for 4 weeks in addition to usual care may help improve fatigue in CFS and ICF patients. Clinical Research Information Service (CRIS) KCT0000508 ; Registered on 12 August 2012.

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The data shown below were compiled from readership statistics for 202 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 <1%
Australia 1 <1%
Unknown 200 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 68 34%
Student > Master 21 10%
Student > Doctoral Student 18 9%
Other 12 6%
Researcher 11 5%
Other 25 12%
Unknown 47 23%
Readers by discipline Count As %
Medicine and Dentistry 78 39%
Nursing and Health Professions 29 14%
Agricultural and Biological Sciences 11 5%
Psychology 8 4%
Biochemistry, Genetics and Molecular Biology 7 3%
Other 16 8%
Unknown 53 26%