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End stage renal disease as a modifier of the periodontal microbiome

Overview of attention for article published in BMC Nephrology, June 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

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1 blog
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Title
End stage renal disease as a modifier of the periodontal microbiome
Published in
BMC Nephrology, June 2015
DOI 10.1186/s12882-015-0081-x
Pubmed ID
Authors

Michel V. Furtado Araújo, Bo-Young Hong, Philip L. Fava, Shiza Khan, Joseph A. Burleson, George Fares, Wilner Samson, Linda D. Strausbaugh, Patricia I. Diaz, Effie Ioannidou

Abstract

Evidence supports high prevalence of periodontitis in patients with chronic kidney disease. Several renal factors have been proposed as possible modifiers of periodontitis pathogenesis in this population. In this cross sectional study, we investigated whether distinct microbial profiles in renal patients could explain high periodontitis prevalence. We characterized the subgingival microbiome in 14 End Stage Renal Disease (ESRD) and 13 control individuals with chronic periodontitis with similar demographic and clinical parameters. Medical, demographic and periodontal parameters were recorded. Subgingival biofilm samples were collected from the deepest pocket in two different quadrants and characterized via 454-pyrosequencing of the 16S rRNA gene. We found 874 species-level operational taxonomic units (OTU) across samples. Renal and control groups did not differ in the individual proportions of periodontitis-associated taxa. However, in principal coordinate plots of distance among samples based on OTU prevalence, some renal patients clustered apart from controls, with the microbial communities of these outlier subjects showing less diversity. Univariate correlation analysis showed a significant negative correlation between dialysis vintage and community diversity. Within the study limitations, dialysis vintage was associated with a less diverse periodontal microbial community in ESRD suggesting the need for further research.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Brazil 1 1%
Unknown 78 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 11%
Student > Master 8 10%
Student > Doctoral Student 7 9%
Student > Bachelor 7 9%
Student > Ph. D. Student 6 8%
Other 21 26%
Unknown 22 28%
Readers by discipline Count As %
Medicine and Dentistry 31 39%
Agricultural and Biological Sciences 7 9%
Biochemistry, Genetics and Molecular Biology 5 6%
Nursing and Health Professions 3 4%
Immunology and Microbiology 2 3%
Other 8 10%
Unknown 24 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2018.
All research outputs
#3,984,640
of 22,818,766 outputs
Outputs from BMC Nephrology
#406
of 2,468 outputs
Outputs of similar age
#50,760
of 266,350 outputs
Outputs of similar age from BMC Nephrology
#5
of 37 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,468 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,350 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.