Title |
Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
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Published in |
BMC Genomics, November 2011
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DOI | 10.1186/1471-2164-12-536 |
Pubmed ID | |
Authors |
Laura Gomez-Valero, Christophe Rusniok, Sophie Jarraud, Benoit Vacherie, Zoé Rouy, Valerie Barbe, Claudine Medigue, Jerome Etienne, Carmen Buchrieser |
Abstract |
Legionella pneumophila is an intracellular pathogen of environmental protozoa. When humans inhale contaminated aerosols this bacterium may cause a severe pneumonia called Legionnaires' disease. Despite the abundance of dozens of Legionella species in aquatic reservoirs, the vast majority of human disease is caused by a single serogroup (Sg) of a single species, namely L. pneumophila Sg1. To get further insights into genome dynamics and evolution of Sg1 strains, we sequenced strains Lorraine and HL 0604 1035 (Sg1) and compared them to the available sequences of Sg1 strains Paris, Lens, Corby and Philadelphia, resulting in a comprehensive multigenome analysis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Sweden | 1 | <1% |
France | 1 | <1% |
Australia | 1 | <1% |
Unknown | 117 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 29 | 24% |
Student > Ph. D. Student | 25 | 20% |
Student > Master | 16 | 13% |
Student > Bachelor | 15 | 12% |
Professor > Associate Professor | 8 | 7% |
Other | 15 | 12% |
Unknown | 14 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 52 | 43% |
Biochemistry, Genetics and Molecular Biology | 26 | 21% |
Immunology and Microbiology | 9 | 7% |
Medicine and Dentistry | 6 | 5% |
Physics and Astronomy | 2 | 2% |
Other | 13 | 11% |
Unknown | 14 | 11% |