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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pathophysiology of cutaneous lupus erythematosus
|
|---|---|
| Published in |
Arthritis Research & Therapy, August 2015
|
| DOI | 10.1186/s13075-015-0706-2 |
| Pubmed ID | |
| Authors |
Jordan C Achtman, Victoria P Werth |
| Abstract |
The pathophysiology of cutaneous lupus erythematosus (CLE) encompasses the complex interactions between genetics, the environment, and cells and their products. Recent data have provided enhanced understanding of these interactions and the mechanism by which they cause disease. A number of candidate genes have been identified which increase the risk of developing CLE. Ultraviolet radiation, the predominant environmental exposure associated with CLE, appears to initiate CLE lesion formation by inducing apoptosis, precipitating autoantigen presentation, and promoting cellular production of specific cytokines. Autoantibodies are a well-known entity in CLE, but their exact role remains unclear. Finally, cells ranging from native skin cells to innate and adaptive immune cells produce cytokines and other molecules and play specific roles in lesion formation and perpetuation. Native skin cells implicated in CLE include keratinocytes and endothelial cells. Innate immune cells crucial to CLE pathophysiology include dendritic cells and neutrophils. The primary adaptive immune cells thought to be involved include Th1 cells, Th17 cells, cytotoxic T cells, and invariant natural killer T cells. Though the pathophysiology of CLE has yet to be fully characterized, current research provides direction for future research and therapies. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 14% |
| Spain | 2 | 9% |
| France | 2 | 9% |
| Ecuador | 1 | 5% |
| Venezuela, Bolivarian Republic of | 1 | 5% |
| Italy | 1 | 5% |
| Australia | 1 | 5% |
| United States | 1 | 5% |
| Unknown | 10 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 68% |
| Practitioners (doctors, other healthcare professionals) | 3 | 14% |
| Science communicators (journalists, bloggers, editors) | 3 | 14% |
| Scientists | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| Unknown | 149 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 24 | 16% |
| Researcher | 15 | 10% |
| Other | 11 | 7% |
| Student > Master | 9 | 6% |
| Student > Postgraduate | 8 | 5% |
| Other | 24 | 16% |
| Unknown | 59 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 36% |
| Immunology and Microbiology | 10 | 7% |
| Agricultural and Biological Sciences | 9 | 6% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Nursing and Health Professions | 3 | 2% |
| Other | 10 | 7% |
| Unknown | 60 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2020.
All research outputs
#3,020,836
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#614
of 3,381 outputs
Outputs of similar age
#37,212
of 275,210 outputs
Outputs of similar age from Arthritis Research & Therapy
#11
of 69 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,210 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.