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Getting the genome in shape: the formation of loops, domains and compartments

Overview of attention for article published in Genome Biology (Online Edition), August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)

Mentioned by

twitter
20 tweeters

Citations

dimensions_citation
99 Dimensions

Readers on

mendeley
303 Mendeley
citeulike
9 CiteULike
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Title
Getting the genome in shape: the formation of loops, domains and compartments
Published in
Genome Biology (Online Edition), August 2015
DOI 10.1186/s13059-015-0730-1
Pubmed ID
Authors

Britta AM Bouwman, Wouter de Laat

Abstract

The three-dimensional folding of the genome has emerged as an important regulatory layer of transcription and is regarded as being pivotal for the establishment and faithful maintenance of cellular identity. The hierarchical levels of genome compaction and folding exert transcriptional control by tuning the accessibility and proximity of genes and cognate regulatory elements. Despite the identification of many factors involved in genome topology, the mechanisms that underlie the establishment of three-dimensional genome architecture and its inheritance through successive cell divisions have remained largely unknown. Here, we review current insights into the chromatin components and associated trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformations.

Twitter Demographics

The data shown below were collected from the profiles of 20 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 303 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 4 1%
United States 3 <1%
United Kingdom 3 <1%
China 2 <1%
Netherlands 1 <1%
France 1 <1%
Italy 1 <1%
Chile 1 <1%
Hungary 1 <1%
Other 7 2%
Unknown 279 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 90 30%
Researcher 73 24%
Student > Master 36 12%
Student > Bachelor 27 9%
Professor 16 5%
Other 32 11%
Unknown 29 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 124 41%
Biochemistry, Genetics and Molecular Biology 106 35%
Computer Science 11 4%
Medicine and Dentistry 7 2%
Physics and Astronomy 6 2%
Other 16 5%
Unknown 33 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2017.
All research outputs
#1,549,747
of 13,847,329 outputs
Outputs from Genome Biology (Online Edition)
#1,427
of 3,073 outputs
Outputs of similar age
#32,981
of 234,819 outputs
Outputs of similar age from Genome Biology (Online Edition)
#2
of 4 outputs
Altmetric has tracked 13,847,329 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,073 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.9. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 234,819 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.