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Outbreak of Marek’s disease in a vaccinated broiler breeding flock during its peak egg-laying period in China

Overview of attention for article published in BMC Veterinary Research, July 2015
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Title
Outbreak of Marek’s disease in a vaccinated broiler breeding flock during its peak egg-laying period in China
Published in
BMC Veterinary Research, July 2015
DOI 10.1186/s12917-015-0493-7
Pubmed ID
Authors

Xinyu Zhuang, Haitao Zou, Huoying Shi, Hongxia Shao, Jianqiang Ye, Ji Miao, Genghua Wu, Aijian Qin

Abstract

Outbreaks of Marek's disease (MD), caused by Marek's disease virus (MDV), primarily occur in 10-12-week-old hens. We report a case of MD in a breeding flock of 24-30-week-old vaccinated broilers in China. The clinical signs in the affected chickens appeared at 24 weeks, and the incidence of tumours peaked at 30 weeks. The morbidity and mortality of the hens were 5 % and 80 %, respectively. Hematoxylin-eosin staining of the tissues showed the typical characteristics of MD. MDV infection was confirmed in the hens with an agar gel diffusion precipitation assay for the MD antigen in the feather follicle epithelium. An MDV strain, designated AH1410, was isolated from the blood lymphocytes. Sequence analyses of the pp38, meq, and gB genes revealed that strain AH1410 had molecular features consistent with a virulent, previously identified MDV. Our data provide evidence that not only is MDV becoming more virulent, but that the period of its onset in chickens is expanding. These findings provide the basis the molecular surveillance and further study of virulent MDV mutants and control strategies for MD in China.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 14%
Researcher 3 14%
Student > Doctoral Student 2 9%
Student > Ph. D. Student 2 9%
Student > Bachelor 2 9%
Other 3 14%
Unknown 7 32%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 4 18%
Biochemistry, Genetics and Molecular Biology 3 14%
Agricultural and Biological Sciences 3 14%
Immunology and Microbiology 2 9%
Nursing and Health Professions 1 5%
Other 2 9%
Unknown 7 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#18,422,065
of 22,821,814 outputs
Outputs from BMC Veterinary Research
#1,922
of 3,050 outputs
Outputs of similar age
#189,492
of 263,720 outputs
Outputs of similar age from BMC Veterinary Research
#46
of 75 outputs
Altmetric has tracked 22,821,814 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,050 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.