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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The suitability of laboratory-bred Anopheles cracens for the production of Plasmodium vivax sporozoites
|
|---|---|
| Published in |
Malaria Journal, August 2015
|
| DOI | 10.1186/s12936-015-0830-0 |
| Pubmed ID | |
| Authors |
Chiara Andolina, Jordi Landier, Verena Carrara, Cindy S Chu, Jean-François Franetich, Alison Roth, Laurent Rénia, Clémentine Roucher, Nick J White, Georges Snounou, François Nosten |
| Abstract |
A stenogamous colony of Anopheles cracens (A. dirus B) established 20 years ago in a Thai insectary proved susceptible to Plasmodium vivax. However, routine sporozoite production by feeding on field-collected blood samples has not been described. The setting-up of an A. cracens colony in an insectary on the Thai-Myanmar border and the process of using P. vivax field samples for the production of infectious sporozoites are described. The colony was started in 2012 from egg batches that were sent from the Department of Parasitology, Faculty of Medicine, University of Chiang Mai, to the Shoklo Malaria Research Unit (SMRU), on wet filter paper in sealed Petri dishes. From May 2013 to December 2014, P. vivax-infected blood samples collected from patients seeking care at SMRU clinics were used for membrane feeding assays and sporozoite production. Mosquitoes were fed on blood samples from 55 patients, and for 38 (69 %) this led to the production sporozoites. The average number of sporozoites obtained per mosquito was 26,112 (range 328-79,310). Gametocytaemia was not correlated with mosquito infectiousness (p = 0.82), or with the number of the sporozoites produced (Spearman's ρ = -0.016, p = 0.905). Infectiousness did not vary with the date of collection or the age of the patient. Mosquito survival was not correlated with sporozoite load (Spearman's ρ = 0.179, p = 0.282). Consistent and routine P. vivax sporozoites production confirms that A. cracens is highly susceptible to P. vivax infection. Laboratory-bred colonies of this vector are suitable for experimental transmission protocols and thus constitute a valuable resource. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 13% |
| Thailand | 1 | 13% |
| Unknown | 6 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 50% |
| Science communicators (journalists, bloggers, editors) | 2 | 25% |
| Scientists | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 3% |
| Unknown | 34 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 34% |
| Student > Ph. D. Student | 5 | 14% |
| Student > Master | 3 | 9% |
| Student > Bachelor | 2 | 6% |
| Other | 2 | 6% |
| Other | 4 | 11% |
| Unknown | 7 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 26% |
| Agricultural and Biological Sciences | 6 | 17% |
| Immunology and Microbiology | 5 | 14% |
| Computer Science | 3 | 9% |
| Biochemistry, Genetics and Molecular Biology | 3 | 9% |
| Other | 1 | 3% |
| Unknown | 8 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2016.
All research outputs
#6,211,081
of 22,821,814 outputs
Outputs from Malaria Journal
#1,723
of 5,565 outputs
Outputs of similar age
#72,116
of 264,494 outputs
Outputs of similar age from Malaria Journal
#27
of 112 outputs
Altmetric has tracked 22,821,814 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 5,565 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,494 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.