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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Targeting dendritic cells in pancreatic ductal adenocarcinoma
|
|---|---|
| Published in |
Cancer Cell International, June 2018
|
| DOI | 10.1186/s12935-018-0585-0 |
| Pubmed ID | |
| Authors |
Anton Deicher, Roland Andersson, Bobby Tingstedt, Gert Lindell, Monika Bauden, Daniel Ansari |
| Abstract |
Dendritic cells (DC) are an integral part of the tumor microenvironment. Pancreatic cancer is characterized by reduced number and function of DCs, which impacts antigen presentation and contributes to immune tolerance. Recent data suggest that exosomes can mediate communication between pancreatic cancer cells and DCs. Furthermore, levels of DCs may serve as prognostic factors. There is also growing evidence for the effectiveness of vaccination with DCs pulsed with tumor antigens to initiate adaptive cytolytic immune responses via T cells. Most experience with DC-based vaccination has been gathered for MUC1 and WT1 antigens, where clinical studies in advanced pancreatic cancer have provided encouraging results. In this review, we highlight the role of DC in the course, prognosis and treatment of pancreatic cancer. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 84 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 25% |
| Researcher | 13 | 15% |
| Student > Master | 8 | 10% |
| Student > Bachelor | 7 | 8% |
| Other | 4 | 5% |
| Other | 9 | 11% |
| Unknown | 22 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 19% |
| Biochemistry, Genetics and Molecular Biology | 15 | 18% |
| Immunology and Microbiology | 10 | 12% |
| Agricultural and Biological Sciences | 9 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 6 | 7% |
| Unknown | 24 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2018.
All research outputs
#14,417,376
of 23,090,520 outputs
Outputs from Cancer Cell International
#737
of 1,822 outputs
Outputs of similar age
#185,268
of 328,114 outputs
Outputs of similar age from Cancer Cell International
#4
of 20 outputs
Altmetric has tracked 23,090,520 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,822 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,114 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.