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Personality disorders do not affect treatment outcomes for chronic HCV infection in Spanish prisoners: the Perseo study

Overview of attention for article published in BMC Infectious Diseases, August 2015
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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7 tweeters

Citations

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3 Dimensions

Readers on

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60 Mendeley
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Title
Personality disorders do not affect treatment outcomes for chronic HCV infection in Spanish prisoners: the Perseo study
Published in
BMC Infectious Diseases, August 2015
DOI 10.1186/s12879-015-1102-x
Pubmed ID
Authors

Andrés Marco, José J. Antón, Joan Trujols, Pablo Saíz de la Hoya, José de Juan, Inmaculada Faraco, Joan A Caylà

Abstract

The link between infection with hepatitis C virus (HCV) and personality disorders (PD) has not been investigated in detail. The aim of this study was to compare the effectiveness of HCV treatment in prisoners with and without PD. We performed a prospective multicentre study in inmates from 25 Spanish prisons who had been treated with pegylated interferon alfa-2a plus ribavirin in 2011. PD diagnosis was based on the Personality Diagnostic Questionnaire-4+. We calculated adjusted Odds Ratios (AOR) and 95 % confidence intervals (95 % CI) using logistic regression. The sample included 236 patients (mean age: 40.3 years, 92.8 % male, 79.2 % intravenous drug users, and 26.3 % HIV-coinfected). The prevalence of PD was 72.5 %. 32.2 % of patients discontinued treatment; this percentage was higher in patients with HCV genotypes 1/4 (AOR = 3.55; CI:1.76-7.18) and those without PD (AOR = 2.51; 1.23-5.11). Treatment discontinuation was mainly for penitentiary reasons (40.3 %): release or transfer between prisons. The rate of sustained viral response (SVR) was 52.1 % by ITT and 76.9 % by observed treatment (OT). SVR was higher among patients with genotype 2 or 3, and those with low baseline HCV-RNA. We did not observe any differences between individuals with and without PD in term of SVR, HCV genotype or HIV infection. Our results support the safety and clinical effectiveness of the treatment of chronic HCV infection in correctional facilities, both in prisoners with PD and those without. Our data support non-discrimination between patients with and without PD when offering treatment for HCV infection to prison inmates. Trial registration number (TRN) NCT01900886 . Date of registration: July 8, 2013.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 20%
Researcher 6 10%
Other 5 8%
Student > Ph. D. Student 5 8%
Student > Bachelor 4 7%
Other 11 18%
Unknown 17 28%
Readers by discipline Count As %
Medicine and Dentistry 10 17%
Social Sciences 10 17%
Psychology 5 8%
Agricultural and Biological Sciences 3 5%
Nursing and Health Professions 3 5%
Other 9 15%
Unknown 20 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2015.
All research outputs
#2,090,198
of 6,315,239 outputs
Outputs from BMC Infectious Diseases
#823
of 2,946 outputs
Outputs of similar age
#64,138
of 193,557 outputs
Outputs of similar age from BMC Infectious Diseases
#52
of 148 outputs
Altmetric has tracked 6,315,239 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 2,946 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,557 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 148 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.