Title |
Outcomes of resections for pancreatic adenocarcinoma with suspected venous involvement: a single center experience
|
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Published in |
BMC Surgery, August 2015
|
DOI | 10.1186/s12893-015-0086-1 |
Pubmed ID | |
Authors |
Christoph W. Michalski, Bo Kong, Carsten Jäger, Silke Kloe, Barbara Beier, Rickmer Braren, Irene Esposito, Mert Erkan, Helmut Friess, Jorg Kleeff |
Abstract |
Pancreatic ductal adenocarcinoma (PDAC) patients frequently present with borderline resectable disease, which can be due to invasion of the portal/superior mesenteric vein (PV/SMV). Here, we analyzed this group of patients, with emphasis on short and long-term outcomes. 156 patients who underwent a resection for PDAC were included in the analysis and sub-stratified into a cohort of patients with PV/SMV resection (n = 54) versus those with standard surgeries (n = 102). While venous resections could be performed safely, there was a trend towards shorter median survival in the PV/SMV resection group (22.7 vs. 15.8 months, p = 0.157). These tumors were significantly larger (3.5 vs 4.3 cm; p = 0.026) and margin-positivity was more frequent (30.4 % vs 44.4 %, p = 0.046). Venous resection was associated with a higher rate of margin positivity and a trend towards shorter survival. However, compared to non-surgical treatment, resection offers the best chance for long term survival. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 4 | 20% |
Researcher | 4 | 20% |
Student > Bachelor | 3 | 15% |
Student > Doctoral Student | 1 | 5% |
Other | 1 | 5% |
Other | 4 | 20% |
Unknown | 3 | 15% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 12 | 60% |
Agricultural and Biological Sciences | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Social Sciences | 1 | 5% |
Engineering | 1 | 5% |
Other | 0 | 0% |
Unknown | 4 | 20% |