↓ Skip to main content

The impact of FSH receptor polymorphism on time-to-pregnancy: a cross-sectional single-centre study

Overview of attention for article published in BMC Pregnancy and Childbirth, June 2018
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

blogs
1 blog

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
32 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The impact of FSH receptor polymorphism on time-to-pregnancy: a cross-sectional single-centre study
Published in
BMC Pregnancy and Childbirth, June 2018
DOI 10.1186/s12884-018-1910-2
Pubmed ID
Authors

Birute Zilaitiene, Marius Dirzauskas, Rasa Verkauskiene, Rytas Ostrauskas, Joerg Gromoll, Eberhard Nieschlag

Abstract

Single nucleotide polymorphism of the follicle-stimulating hormone (FSH) receptor (FSHR) is an important marker of ovarian function. However, its role in female fecundity remains debatable. The aim of the study to assess the relationship of FSHR polymorphism of Serine/Serine, Asparagine/Asparagine and Asparagine/Serine variants directly against the time-to-pregnancy (TTP) in women. Data were collected from 291 consecutive selected post-partum Caucasians using this criterion: ethnicity, age between 21 and 34-year-old new mothers and, 0-3 days after delivery of newborns in the Klaipeda University Hospital, Lithuania. Questionnaires on factors associated with conception were given to patients, and blood samples were collected for genomic DNA extractions as well as for analysis of follicle-stimulating hormone receptor gene polymorphism. Odds ratios (OR) and 95% confidence intervals (CI) for time-to-pregnancy were estimated by multivariate logistic regression. Women with unplanned pregnancies and those who received assisted reproductive technologies were not included in the study. After adjustment for other possible factors, increased risk for time-to-pregnancy of 12 or more months was associated with: Serine/Serine polymorphism variant (OR = 1.38, 95% CI 1.56-2.71, p = 0.007), age of 30 or more years (OR = 1.95, 95% CI 1.25-2.71, p = 0.015), gynaecological diseases in the past (OR = 2.21, 95% CI 1.12-5.74, p = 0.027), prior contraception use (OR = 1.87, 95% CI 1.14-3.64, p = 0.016), and fertility problems in the past (OR = 1.57, 95% CI 1.16-4.76, p = 0.019). The results suggest a possible relationship of FSH receptor gene Serine/Serine variant for the lower possibility of conception during the first 12 months of planned conception.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 13%
Student > Postgraduate 3 9%
Student > Ph. D. Student 3 9%
Professor 2 6%
Researcher 2 6%
Other 5 16%
Unknown 13 41%
Readers by discipline Count As %
Medicine and Dentistry 5 16%
Nursing and Health Professions 3 9%
Biochemistry, Genetics and Molecular Biology 3 9%
Psychology 3 9%
Physics and Astronomy 1 3%
Other 3 9%
Unknown 14 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2018.
All research outputs
#5,829,518
of 23,092,602 outputs
Outputs from BMC Pregnancy and Childbirth
#1,514
of 4,252 outputs
Outputs of similar age
#100,174
of 329,253 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#54
of 131 outputs
Altmetric has tracked 23,092,602 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,252 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,253 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.