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Plasmablastic lymphoma in Malawi

Overview of attention for article published in Infectious Agents and Cancer, June 2018
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Title
Plasmablastic lymphoma in Malawi
Published in
Infectious Agents and Cancer, June 2018
DOI 10.1186/s13027-018-0195-4
Pubmed ID
Authors

Takondwa Zuze, Matthew S. Painschab, Ryan Seguin, Evarista Kudowa, Bongani Kaimila, Edwards Kasonkanji, Tamiwe Tomoka, Bal Mukunda Dhungel, Maurice Mulenga, Maria Chikasema, Blessings Tewete, Asekanadziwa Ntangwanika, Sarah Chiyoyola, Fred Chimzimu, Coxcilly Kampani, Robert Krysiak, Nathan D. Montgomery, Yuri Fedoriw, Satish Gopal

Abstract

Plasmablastic lymphoma (PBL) clinical descriptions are scarce from sub-Saharan Africa (SSA) where both HIV and EBV are highly endemic. We identified 12 patients with pathologically confirmed PBL from a prospective cohort in Lilongwe, Malawi. Median age was 46 (range 26-71), seven (58%) were male, and six (50%) were HIV-positive. Eight patients were treated with CHOP and four with a modified EPOCH regimen. One-year overall survival was 56% (95% CI 24-79%), without clear differences based on HIV status. PBL occurs in Malawi in HIV-positive and HIV-negative individuals and can be treated successfully with curative intent, even in a low-resource setting in SSA.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 12%
Student > Postgraduate 3 12%
Researcher 3 12%
Librarian 1 4%
Student > Bachelor 1 4%
Other 3 12%
Unknown 12 46%
Readers by discipline Count As %
Medicine and Dentistry 13 50%
Nursing and Health Professions 1 4%
Unspecified 1 4%
Unknown 11 42%