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Mendeley readers
| Title |
Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in lung cell cultures from different avian species
|
|---|---|
| Published in |
Virology Journal, September 2011
|
| DOI | 10.1186/1743-422x-8-447 |
| Pubmed ID | |
| Authors |
Haijun Jiang, Hanchun Yang, Darrell R Kapczynski |
| Abstract |
Type I interferons, including interferon alpha (IFN-α), represent one of the first lines of innate immune defense against influenza virus infection. Following natural infection of chickens with avian influenza virus (AIV), transcription of IFN-α is quickly up regulated along with multiple other immune-related genes. Chicken IFN-α up regulates a number of important anti-viral response genes and has been demonstrated to be an important cytokine to establish anti-viral immunity. However, the mechanisms by which interferon inhibit virus replication in avian species remains unknown as does the biological activity of chicken interferon in other avian species. |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 1% |
| Unknown | 71 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 22% |
| Researcher | 11 | 15% |
| Student > Master | 10 | 14% |
| Student > Bachelor | 5 | 7% |
| Student > Doctoral Student | 3 | 4% |
| Other | 10 | 14% |
| Unknown | 17 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 36% |
| Veterinary Science and Veterinary Medicine | 9 | 13% |
| Immunology and Microbiology | 8 | 11% |
| Biochemistry, Genetics and Molecular Biology | 4 | 6% |
| Medicine and Dentistry | 4 | 6% |
| Other | 6 | 8% |
| Unknown | 15 | 21% |