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X Demographics
Mendeley readers
| Title |
Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation
|
|---|---|
| Published in |
BMC Chemistry, November 2011
|
| DOI | 10.1186/1752-153x-5-70 |
| Pubmed ID | |
| Authors |
Mohamed I Walash, Fathallah F Belal, Nahed M El-Enany, Mahmoud H El-Maghrabey |
| Abstract |
A rapid, simple and sensitive synchronous specrtofluorimetric method has been developed for the simultaneous analysis of binary mixture of metoprolol (MTP) and felodipine (FDP). The method is based upon measurement of the synchronous fluorescence intensity of the two drugs at Δλ of 70 nm in aqueous solution. The different experimental parameters affecting the synchronous fluorescence intensities of the two drugs were carefully studied and optimized. The fluorescence intensity-concentration plots were rectilinear over the ranges of 0.5-10 μg/mL and 0.2-2 μg/mL for MTP and FDP, respectively. The limits of detection were 0.11 and 0.02 μg/mL and quantification limits were 0.32 and 0.06 μg/mL for MTP and FDP, respectively. The proposed method was successfully applied for the determination of the two compounds in their commercial tablets and the results obtained were favorably compared to those obtained with a comparison method. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 27 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 15% |
| Student > Master | 4 | 15% |
| Professor | 3 | 11% |
| Researcher | 2 | 7% |
| Lecturer | 2 | 7% |
| Other | 5 | 19% |
| Unknown | 7 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 9 | 33% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 11% |
| Engineering | 2 | 7% |
| Medicine and Dentistry | 2 | 7% |
| Environmental Science | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 8 | 30% |